Kinetics of eosinophilia and IGE production in experimental murine toxocariasis

المؤلفون المشاركون

Hafiz, Adil Umar
al-Shazli, Atif M.
al-Shaykhah, Hani M.
Mursi, Tusun Ali
al-Beshbishi, Samar N.

المصدر

Journal of the Egyptian Society of Parasitology

العدد

المجلد 38، العدد 1 (30 إبريل/نيسان 2008)، ص ص. 53-64، 12ص.

الناشر

الجمعية المصرية لعلم الطفيليات

تاريخ النشر

2008-04-30

دولة النشر

مصر

عدد الصفحات

12

التخصصات الرئيسية

الطب البشري

الموضوعات

الملخص EN

Eosinophilia and immunoglobulin E (IgE) antibody are considered the first and important elements in host responses to helminth in-fection.

Toxocara canis, which elicits prominent eosinophilia and IgE production in normal mice, may be useful in understanding the kinetics of circulating peripheral blood eosinophils and IgE antibody during infection.

The onset, magnitude and duration of peripheral blood eosinophilia and total IgE production after primary T.

canis in-fection in female outbred albino mice was investigated.

Mice were either sham inoculated (controls) or were orally infected with 1000 embryonated eggs of T.

canis.

Patterns in leucocytic changes include significant increase in total WBC count between weeks 6 and 13 post infection (PI) with a peak on week 8 PI.

Mice showed eosinophilia between weeks 2 to 17 PI with a peak on week 7.

The development of eosinophilia in T.

canis-infected mice was accompanied by the relea-se of prominent level of serum IgE between weeks 2 to 21 with a peak at week 6 PI.

These findings showed that eosinophilia in T.

canis infected outbred mice can be T-cell dependent.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

al-Shaykhah, Hani M.& al-Beshbishi, Samar N.& al-Shazli, Atif M.& Hafiz, Adil Umar& Mursi, Tusun Ali. 2008. Kinetics of eosinophilia and IGE production in experimental murine toxocariasis. Journal of the Egyptian Society of Parasitology،Vol. 38, no. 1, pp.53-64.
https://search.emarefa.net/detail/BIM-280141

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

al-Shaykhah, Hani M.…[et al.]. Kinetics of eosinophilia and IGE production in experimental murine toxocariasis. Journal of the Egyptian Society of Parasitology Vol. 38, no. 1 (Apr. 2008), pp.53-64.
https://search.emarefa.net/detail/BIM-280141

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

al-Shaykhah, Hani M.& al-Beshbishi, Samar N.& al-Shazli, Atif M.& Hafiz, Adil Umar& Mursi, Tusun Ali. Kinetics of eosinophilia and IGE production in experimental murine toxocariasis. Journal of the Egyptian Society of Parasitology. 2008. Vol. 38, no. 1, pp.53-64.
https://search.emarefa.net/detail/BIM-280141

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references : p. 62-64

رقم السجل

BIM-280141