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Differential therapeutic approach in patients with clinical stage of nonseminomatous germ cell testicular tumors Long-term experience
المؤلفون المشاركون
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 10، العدد 3 (31 يوليو/تموز 2008)، ص ص. 163-168، 6ص.
الناشر
تاريخ النشر
2008-07-31
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : surveillance after orchiectomy alone has become popular for the management of clinical stage nonseminomatous germ cell tumors of the testis (CS I NSGCTT).
Efforts to identify patients at high risk of relapse led to a search for prognostic factors of CS I NSGCTT.
The aim of this study was to analyses long-term experiences with different therapeutic approaches in CS I NSGCTT patients according to relapse risk factors.
Methods : from 2 / 1992 to 5 / 2008, a total of 352 CS I NSGCTT patients were included in the study and stratified into different risk-adapted therapeutic approaches (groups 1-3).
114 patients (group 1) with vascular invasion and majority of embryonic carcinoma component in the primary tumor were treated with 2 cycles of BEP chemotherapy.
Results : relapse was experienced in 2 patients (1.75 %).
Among 12 patients (group 2) with vascular invasion and majority of teratomatous elements in the primary tumor undergoing primary retroperitoneal lymph node dissection (RPLND), 10 were found to be in pathological stage I.
Relapse was observed in two patients (16.7 %).
One of whom died 29 months following orchiectomy.
Two patients (18.2 %) with pathological stage II received adjuvant chemotherapy and finally died.
226 patients (group 3) without vascular invasion were followed after orchiectomy.
Relapse was observed in 41 patients (18.1 %).
They were treated with BEP chemotherapy, which three died.
The overall survival rate of all the patients in group B1-3 was 98.3 %.
Conclusion : surveillance procedure is recommended only in patients without vascular invasion in the primary tumor.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ondrus, D.& Ondrusova, M.. 2008. Differential therapeutic approach in patients with clinical stage of nonseminomatous germ cell testicular tumors Long-term experience. Iranian Red Crescent Medical Journal،Vol. 10, no. 3, pp.163-168.
https://search.emarefa.net/detail/BIM-28186
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ondrus, D.& Ondrusova, M.. Differential therapeutic approach in patients with clinical stage of nonseminomatous germ cell testicular tumors Long-term experience. Iranian Red Crescent Medical Journal Vol. 10, no. 3 (Jul. 2008), pp.163-168.
https://search.emarefa.net/detail/BIM-28186
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ondrus, D.& Ondrusova, M.. Differential therapeutic approach in patients with clinical stage of nonseminomatous germ cell testicular tumors Long-term experience. Iranian Red Crescent Medical Journal. 2008. Vol. 10, no. 3, pp.163-168.
https://search.emarefa.net/detail/BIM-28186
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 167-168
رقم السجل
BIM-28186
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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