Synthesis of histidine-amoxillin condensed drug polymer

الملخص EN

A novel drug polymer as a peptid-biopolymer was prepared from histidineacidchloride with amoxillinacidchloride, the condensed polymer was prepared with molar ratio 1 : 1, this biocompatible, biodegradable, reabsorb able condensed polymers with controlled lifetimes, which can be used as drug carrier polymer.

The physical properties were measured and the intrinsic viscosity was measured using Ostwald viscometer, The controlled release rates were studied in different pH values at 37 0C.

The condensed polymer was characterized by UV-vis.

FTIR and 1H-NMR spectroscopy, This biomaterial polymer can be used as non-toxic substance.

When it undergo hydrolytic degradation.