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Physiological and anatomical studies on the effect of salvia officinalis on the blood and pancreas in normal and streptozotocin-induced diabetic rats
العناوين الأخرى
دراسة تشريحية و فسيولوجية لتأثير نبات الميرمية على الدم و البنكرياس على الجرذان السليمة و الجرذان المصابة بمرض البول السكري المستحدث
مقدم أطروحة جامعية
مشرف أطروحة جامعية
al-Tamimi, Husam Jamal
al-Shakanbah, Jumah Muti
أعضاء اللجنة
Sad al-Din, Raja Abd al-Razzaq
Atruz, Umar Muhammad Falih
الجامعة
جامعة مؤتة
الكلية
كلية العلوم
القسم الأكاديمي
قسم الأحياء
دولة الجامعة
الأردن
الدرجة العلمية
ماجستير
تاريخ الدرجة العلمية
2009
الملخص الإنجليزي
The leaves of Salvia officinalis (Sg) are known to have a wide range of biological effects including antibacterial, fungistatic and virustatic, and has long been used within the domain of alternative medicine in human therapy.
Three experiments were carried out using a total of 108 male adult albino rats to study different physiological and anatomical parameters on the effect of Sg on selected blood biochemical parameters and pancreas in normal and sreptozotocin (St) induced-diabetic rats.
In the first experiment, Sg (methanolic extract) was administered intraperitoneally in (12) rats, for a total of 35 days in St-treated and/or untreated rats.
A significant decrease in glucose, triglyceride, cholesterol and uric acid, while no significant change in albumin, ALAT, ASAT, creatinine, total protein, alkaline phosphatase, urea, calcium, sodium, potassium, billirubin, and creatinine kinase in treated diabetic induced rats compared with untreated diabetic rats.
In the second experiment, Sg (methanolic extract) was administered in drinking water in (12) rats, for a total of 32 days in St-treated and/or untreated rats.
There was a significant decrease in glucose and cholesterol levels, while there was no significant change in other parameters in treated diabetic rats compared with untreated diabetic rats.
In the third experiment, Sg (water extract) was administered in drinking water in 30 rats, for a total of 30 days in St-treated and/or untreated rats.
Treatment with Sg for 15 days showed a significant decrease in glucose, creatinine and albumin level, in treated diabetic rats compared with untreated diabetic rats.
Treatment with Sg for 30 days showed a significant decrease in glucose, creatinine, urea levels, while there was a significant increase in albumin and calcium values in treated diabetic rats compared with untreated diabetic rats.
Histopathological study showed a total increase in the number of langerhans islets in treated diabetic rats.
التخصصات الرئيسية
الموضوعات
عدد الصفحات
93
قائمة المحتويات
Table of contents.
Abstract.
Abstract in Arabic.
Chapter one : Theoretical background.
Chapter two : Literature review.
Chapter three : Materials and methods.
Chapter four : Results.
Chapter five : Discussion, conclusion and recommendations.
References.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Uran, Tasnim Mufaddi. (2009). Physiological and anatomical studies on the effect of salvia officinalis on the blood and pancreas in normal and streptozotocin-induced diabetic rats. (Master's theses Theses and Dissertations Master). Mutah University, Jordan
https://search.emarefa.net/detail/BIM-304959
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Uran, Tasnim Mufaddi. Physiological and anatomical studies on the effect of salvia officinalis on the blood and pancreas in normal and streptozotocin-induced diabetic rats. (Master's theses Theses and Dissertations Master). Mutah University. (2009).
https://search.emarefa.net/detail/BIM-304959
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Uran, Tasnim Mufaddi. (2009). Physiological and anatomical studies on the effect of salvia officinalis on the blood and pancreas in normal and streptozotocin-induced diabetic rats. (Master's theses Theses and Dissertations Master). Mutah University, Jordan
https://search.emarefa.net/detail/BIM-304959
لغة النص
الإنجليزية
نوع البيانات
رسائل جامعية
رقم السجل
BIM-304959
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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