Virologic response at week 8 of combined treatment as a predictor of sustained virologic response in non rapid virologic response, chronic HCV genotype 4 infected patients
المؤلفون المشاركون
al-Sawwaf, Riham
Munis, Ali
Munis, Ahmad Ali
المصدر
The Egyptian Journal of Medical Human Genetics
العدد
المجلد 13، العدد 3 (31 ديسمبر/كانون الأول 2012)، ص ص. 331-335، 5ص.
الناشر
الجمعية المصرية للأمراض الوراثية
تاريخ النشر
2012-12-31
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Optimization of interferon-based treatment regimens remains an important goal as regulated interferon is likely to remain the backbone of chronic HCV treatment in the foreseeable future.
The objective of the current study was to evaluate virological response at week 8 of combined treatment as a predictor of sustained virology response (SVR) in non-rapid virology response (RVR), chronic HCV genotype 4 infected patients.
A total of 38 patients with chronic HCV genotype 4 infection were enrolled in the study.
All patients received a combination of pegylated interferon a-2a plus ribavirin.
Virological response at week 8 of combined treatment was evaluated as a predictor of SVR.
Week 8 response was more sensitive but less specific than RVR in predicting SVR, in non RVR patients (24 patients), week 8 response had a sensitivity of 45.5 % and a specificity of 76.9 % for predicting SVR.
In conclusion : in non RVR patients, measurement of HCV RNA at week 8 is an optimal time to identify those who are not going to benefit from pegylated interferon and ribavirin combination therapy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Munis, Ali& Munis, Ahmad Ali& al-Sawwaf, Riham. 2012. Virologic response at week 8 of combined treatment as a predictor of sustained virologic response in non rapid virologic response, chronic HCV genotype 4 infected patients. The Egyptian Journal of Medical Human Genetics،Vol. 13, no. 3, pp.331-335.
https://search.emarefa.net/detail/BIM-313049
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Munis, Ali…[et al.]. Virologic response at week 8 of combined treatment as a predictor of sustained virologic response in non rapid virologic response, chronic HCV genotype 4 infected patients. The Egyptian Journal of Medical Human Genetics Vol. 13, no. 3 (2012), pp.331-335.
https://search.emarefa.net/detail/BIM-313049
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Munis, Ali& Munis, Ahmad Ali& al-Sawwaf, Riham. Virologic response at week 8 of combined treatment as a predictor of sustained virologic response in non rapid virologic response, chronic HCV genotype 4 infected patients. The Egyptian Journal of Medical Human Genetics. 2012. Vol. 13, no. 3, pp.331-335.
https://search.emarefa.net/detail/BIM-313049
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 335
رقم السجل
BIM-313049
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر