Evaluation of HbA1c and oxidation status in diabetic patients (type 2)‎ in Erbil Governorate

العناوين الأخرى

تقييم HbA1c و حالة الأكسدة لدى مرضى السكري من النوع الثاني في محافظة أربيل

مقدم أطروحة جامعية

Jafar, Sarwar Nawzad

مشرف أطروحة جامعية

Nanakali, Nadir Mustafa Qadir

أعضاء اللجنة

Ahmad, Sardar Nuri
Mawlud, Kulthum Assaf
Kakei, Ismail Salih Ibrahim

الجامعة

جامعة صلاح الدين

الكلية

كلية العلوم

القسم الأكاديمي

قسم علم الأحياء

دولة الجامعة

العراق

الدرجة العلمية

ماجستير

تاريخ الدرجة العلمية

2012

الملخص الإنجليزي

This study was carried out in Layla Qasim center for diabetic patients in Erbil governorate, from the period of December 2010 to June 2011.

Fasting blood samples were obtained from one hundred fifty two diabetic patients (59 males and 93 females) of type 2 and 50 apparently clinically healthy individuals were selected as a normal group (29 males and 21 females).

In this study, some physiological and biochemical parameters were determined in patients and normal group.

Then the results were compared between diabetic patients and normal group.

The results showed that the mean body mass index of diabetic patients (29.92) kg / m2 was significantly higher (P < 0.05) than that of normal group (27.48) kg / m2 and waist circumference in diabetic patients had significantly higher mean (100.82) cm than normal group (95) cm and mean HbA1c percentage were significantly higher in diabetic patients (9.18) % than normal group percentage (5.57) %.

The results revealed no significant difference (P > 0.05) in mean Erythrocyte sedimentation rate between diabetic patients and normal group with respect to blood pressure difference, the result showed significant difference in diastolic blood pressure in diabetic group compared to normal group, while systolic blood pressure showed non significance difference.

Significant increase observed in lipid profile between diabetic patients compared to normal group (Total cholesterol, LDL, VLDL and Triglyceride), while HDL level showed significant decrease in diabetic patients.

Results showed that mean serum Superoxide dismutase activity in diabetic (0.202) IU / L was significantly higher than normal (0.123) IU / L groups.

While mean serum glutathione levels (37.726) μmol / L was significantly lower in diabetic patients, than in normal group (42.931) μmol / L.

beyond that mean vitamin E (9.9) μmol / L was significantly lower in diabetic patients, than normal II group (15.6) μmol / L.

The results revealed high level were of serum MDA (1.60) μmol / L in diabetic patients compared to in normal group (1.27) μmol / L.

In matter of comparisons according to gender, most of parameters showed no significant and only few show significant difference between males and females in diabetic group and normal group.

التخصصات الرئيسية

الأحياء

الموضوعات

• مرض السكري
• العراق
• أربيل

عدد الصفحات

87

قائمة المحتويات

• APA
• MLA
• AMA

لغة النص

الإنجليزية

نوع البيانات

رسائل جامعية

رقم السجل

BIM-314563