Analysis of the short tandem repeats (STRs)‎ of Y-chromosome among the population of Algeria

مقدم أطروحة جامعية

Ghania, Djekrif

مشرف أطروحة جامعية

Mahasinah, Ihsan

أعضاء اللجنة

al-Khawlidah, Rida Abd Allah Urayq Shibli
Irshaid, Fawzi
Mansi, Kamal M.

الجامعة

جامعة آل البيت

الكلية

كلية العلوم

القسم الأكاديمي

قسم العلوم الحياتية

دولة الجامعة

الأردن

الدرجة العلمية

ماجستير

تاريخ الدرجة العلمية

2011

الملخص الإنجليزي

The short Tandem Repeat (STRs) found on the mal specific Y- chromosome and being used in human genealogy.

This study reports the first data on Y- chromosome specific short tandem repeats (STRs) allele frequencies, haplotype frequencies and minimal haplotype for seventeen Y-STRs locus (DYS456-DYS389I-DYS 390-DYS 389II-DYS458- DYS19- DYS 385a-DYS 385b-DYS393-DYS391-H4 DYS439-DYS635-DYS392-DYS437-DYS 438-DYS 448), were determined in population from Algeria.

DNA samples from 30 unrelated males were analyzed by using the multiplex polymerase chain reaction (PCR), the allele patterns were detected by using the fluorescent detector of an automated DNA analyzer (GA310, Applied Biosystem,USA) The observed number of alleles varied from 0 to 31 alleles per locus, from the data all seventeen loci were highly polymorphic.

The gene diversity of the alleles among Algeria wilaya ranged from minimum of 0.132 for (DYS392) to a maximum of 0.867 for (DYS3 85a).

A total of 29 different haplotypes were identified by the seventeen Y-STR loci.

The overall haplotype diversity was 0.99.

Wherever the minimal haplotype (calculated manually> 75) is composed of three Y-STRS (DYS389II-DYS392-DYS448), which were observed in the Algeria samples equivalent to most commonly loci.

In conclusion, the data of allele frequency for the whole loci is considered a good tool to identify Algerian and also the primary step to establish a primary DNA data base.

التخصصات الرئيسية

الأحياء

الموضوعات

عدد الصفحات

110

قائمة المحتويات

Table of contents.

Abstract.

Chapter One : introduction.

Chapter Two : material and methods.

Chapter Three : results and discussion.

References.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Ghania, Djekrif. (2011). Analysis of the short tandem repeats (STRs) of Y-chromosome among the population of Algeria. (Master's theses Theses and Dissertations Master). Al albayt University, Jordan
https://search.emarefa.net/detail/BIM-321690

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Ghania, Djekrif. Analysis of the short tandem repeats (STRs) of Y-chromosome among the population of Algeria. (Master's theses Theses and Dissertations Master). Al albayt University. (2011).
https://search.emarefa.net/detail/BIM-321690

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Ghania, Djekrif. (2011). Analysis of the short tandem repeats (STRs) of Y-chromosome among the population of Algeria. (Master's theses Theses and Dissertations Master). Al albayt University, Jordan
https://search.emarefa.net/detail/BIM-321690

لغة النص

الإنجليزية

نوع البيانات

رسائل جامعية

رقم السجل

BIM-321690