Histopathological evaluation of bone healing using nanobone in experimentally induced frontal bone defects of rabbits
المؤلفون المشاركون
Jabir, Ala S.
al-Sudani, Kazim A.
المصدر
Journal of Baghdad College of Dentistry
العدد
المجلد 24، العدد 4 (31 ديسمبر/كانون الأول 2012)، ص ص. 40-45، 6ص.
الناشر
تاريخ النشر
2012-12-31
دولة النشر
العراق
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : The bone substitute biomaterials are used in reconstruction of bone defects and one of them is Nanobone.
It consists of nanocrystalline hydroxyapatite embedded in a highly porous matrix of silica gel.
It promotes the healing of bone defects and increases the amount of new bone formed.
It is degraded and resorbed by osteoclasts after a period of time.
The aim of study was to evaluate the effects of Nanobone on bone healing in experimentally frontal bony defects of rabbits. Materials and Methods : Thirty five indigenous rabbits were used in this study.
Granules of Nanobone were implanted in surgically induced defects of 5mm size in one side in the frontal bone of rabbits, while the other side defects were left free to heal spontaneously as controls.
Samples were taken after 2, 6, 9, 12 and 24 weeks and demineralized.
The amount of new bone formed around implanted granules and the inflammation present were analyzed by means of light microscopy in both Nanobone granules-filled defects and controls. Results : At 2 weeks, there was no new bone formed in both defects with few amount of inflammation which considers normal at this time.
At 6, 9 and 12 weeks , the amount of new bone formed in Nanobone filled defects was much more than that formed in controls (statistically significant correlation, P < 0.05), no inflammation seen in boths.
At 24 weeks, the Nanobone granules were degraded and completely replaced by new bone while in controls there was few spaces not filled with bone (statistically highly significant correlation, P < 0.01), no inflammation seen also. Conclusions : Results of present study revealed that Nanobone material promotes healing of bony defects in comparison to controls and is degraded and replaced by new bone after a period of time.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jabir, Ala S.& al-Sudani, Kazim A.. 2012. Histopathological evaluation of bone healing using nanobone in experimentally induced frontal bone defects of rabbits. Journal of Baghdad College of Dentistry،Vol. 24, no. 4, pp.40-45.
https://search.emarefa.net/detail/BIM-324146
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jabir, Ala S.& al-Sudani, Kazim A.. Histopathological evaluation of bone healing using nanobone in experimentally induced frontal bone defects of rabbits. Journal of Baghdad College of Dentistry Vol. 24, no. 4 (2012), pp.40-45.
https://search.emarefa.net/detail/BIM-324146
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jabir, Ala S.& al-Sudani, Kazim A.. Histopathological evaluation of bone healing using nanobone in experimentally induced frontal bone defects of rabbits. Journal of Baghdad College of Dentistry. 2012. Vol. 24, no. 4, pp.40-45.
https://search.emarefa.net/detail/BIM-324146
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 45
رقم السجل
BIM-324146
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر