The significance of angiogenesis in the biological behavior of colorectal carcinoma and its metastatic lymph nodes using CD34 antibody
المؤلفون المشاركون
Hammudi, Salim R.
Muhammad, Daliya R.
المصدر
العدد
المجلد 12، العدد 2 (31 ديسمبر/كانون الأول 2009)، ص ص. 267-272، 6ص.
الناشر
تاريخ النشر
2009-12-31
دولة النشر
العراق
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
A retrospective histopathological study was carried on 31 cases of colorectal adenocarcinoma using the paraffin embedded tissue sections and 10 cases negative from malignancy (colitis).
The aims of this study were to study the angiogenesis in colorectal carcinoma and in regional L.N with positive metastasis and assessing the micro vascular density (MVD) as a marker of angiogenesis and estimate the correlation of angiogenesis with various clinic pathological parameters.
Results MVD significantly correlated with the type of lesion with a higher mean in malignant cases 19.73 in comparison to nonmalignant cases (6.4) mean MVD in metastatic L.N (19) while in non-metastatic L.N(follicular hyperplasia) was 8.5.
Significant correlation was found between MVD and site of the tumor in favor of left site, significant correlation was found between MVD and pathological grading, Regarding staging system (modified Astler-coller) staging system significant correlation was also found.
A higher mean MVD in CRC with metastasized L.N (24.8).while in non-metastatic CRC it was (19.6).
conclusions : Assessment of tumor vascularity (MVD) by immunohistochemical staining method using CD34 is a useful way to quantify angiogenesis in CRC.
MVD is an important parameter to assess the malignant behavior of the lesion, as it is found to be higher in malignant cases than the non–malignant ones.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hammudi, Salim R.& Muhammad, Daliya R.. 2009. The significance of angiogenesis in the biological behavior of colorectal carcinoma and its metastatic lymph nodes using CD34 antibody. Kufa Medical Journal،Vol. 12, no. 2, pp.267-272.
https://search.emarefa.net/detail/BIM-327215
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hammudi, Salim R.& Muhammad, Daliya R.. The significance of angiogenesis in the biological behavior of colorectal carcinoma and its metastatic lymph nodes using CD34 antibody. Kufa Medical Journal Vol. 12, no. 2 (2009), pp.267-272.
https://search.emarefa.net/detail/BIM-327215
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hammudi, Salim R.& Muhammad, Daliya R.. The significance of angiogenesis in the biological behavior of colorectal carcinoma and its metastatic lymph nodes using CD34 antibody. Kufa Medical Journal. 2009. Vol. 12, no. 2, pp.267-272.
https://search.emarefa.net/detail/BIM-327215
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 271-272
رقم السجل
BIM-327215
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر