Idiopathic autoimmune thrombocytopenic purpura (ITP) in adult ; review of 50 cases admitted to Baghdad teaching hospital
المؤلفون المشاركون
Ulwan, Ala Fadil
al-Uqbi, Adil S.
المصدر
Journal of the Faculty of Medicine Baghdad
العدد
المجلد 52، العدد 2 (30 يونيو/حزيران 2010)، ص ص. 167-171، 5ص.
الناشر
تاريخ النشر
2010-06-30
دولة النشر
العراق
عدد الصفحات
5
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : Idiopathic autoimmune thrombocytopenia purpura (ITP) is an isolated thrombocytopenia in a patient with no clinically apparent associated conditions or factors that can cause thrombocytopenia.
The syndrome of ITP is caused by platelet-specific auto-antibodies that bind to autologous platelets.
The diagnosis of ITP is usually a diagnosis of exclusion based on a demonstration of peripheral thrombocytopenia.
Steroids are the conventional first-line therapy for adult ITP.
Most patients demonstrate a response to steroids within 2 to 4 weeks, but a late response is possible. Patients and Methods : A prospective study on 50 patients with diagnosis consistent with ITP, initially treated by steroid, patients who were non responders to steroids or relapsed following its withdrawal offered splenectomy Results : Ten patients (20 %) had permanent satisfactory remission following steroid therapy, while other 40 patients (80 %) were either non responders (20 patients, 40 %) or relapsed (20 patients, 40 %).
Twenty patients (40 %) underwent splenectomy, all of them initially responded, after 3-6 months, 17 patients of them (85 %) were still in complete remission, while 3 patients (15 %) were refractory ITP and required further treatment. Conclusion : Steroid therapy is less effective in achieving satisfactory remission in adult patient with ITP ; on the other hand, splenectomy had more sustained response after steroid failure.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Uqbi, Adil S.& Ulwan, Ala Fadil. 2010. Idiopathic autoimmune thrombocytopenic purpura (ITP) in adult ; review of 50 cases admitted to Baghdad teaching hospital. Journal of the Faculty of Medicine Baghdad،Vol. 52, no. 2, pp.167-171.
https://search.emarefa.net/detail/BIM-335819
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Uqbi, Adil S.& Ulwan, Ala Fadil. Idiopathic autoimmune thrombocytopenic purpura (ITP) in adult ; review of 50 cases admitted to Baghdad teaching hospital. Journal of the Faculty of Medicine Baghdad Vol. 52, no. 2 (2010), pp.167-171.
https://search.emarefa.net/detail/BIM-335819
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Uqbi, Adil S.& Ulwan, Ala Fadil. Idiopathic autoimmune thrombocytopenic purpura (ITP) in adult ; review of 50 cases admitted to Baghdad teaching hospital. Journal of the Faculty of Medicine Baghdad. 2010. Vol. 52, no. 2, pp.167-171.
https://search.emarefa.net/detail/BIM-335819
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 170-171
رقم السجل
BIM-335819
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر