Homestasis model assessment-adiponectin ratio and adiponectin-resistin index as markers of insulin resistance in type 2 diabetes mellitus
المؤلفون المشاركون
Hamid, Ikhlas Khalid
Rashid, Nada F.
Ubayd, Bayda A.
المصدر
Journal of the Faculty of Medicine Baghdad
العدد
المجلد 55، العدد 2 (30 يونيو/حزيران 2013)، ص ص. 175-178، 4ص.
الناشر
تاريخ النشر
2013-06-30
دولة النشر
العراق
عدد الصفحات
4
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : insulin resistance (IR) is an important clinical and biochemical determinant of diabetes and many other clinical states.
The gold standard method for IR estimation is the hyperinsulinemic euglycaemic glucose clamp.
Adiponectin and resistin are adipocytes derived hormones that play important role in the regulation of glucose, fat metabolism and insulin resistance.
Objective : this study aimed to assess the validity of Homestasis Model Assessment-Adiponectin ratio and Adiponectin–Resistin index as markers of insulin resistance in type 2 diabetic mellitus (T2DM) patients.
Design : Ninety (T2DM) overweight male subjects were enrolled in this cross sectional study, detailed history, physical examination and anthropometric measures including BMI, waist, and hip circumference were done to all the participants.
Fasting serum samples were obtained and used for the measurement of serum glucose, serum triglyceride, high density lipoprotein(HDL), very low density lipoprotein(VLDL), HbA1c, also serum insulin, adiponectin, resistin were measured and HOMA-IR, HOMA-AD and AR-index were calculated.SPSS-17 was used to analyze the data.
Results : AR-index correlates significantly with FSG, Fasting Insulin and HOMA-IR (r = 0.534.p = 0.005), (r = 0.545, p = 0.005), (r = 0.506, p = 0.008) respectively HOMA-AD correlates with FSG (R = 0.551, P = 0.001), insulin (P = 0.956,p = 0.000), HOMA-IR (r = 0.952, p = 0.000).
AUC for AR-index (0.800) and for HOMA-AD (0.905).
Conclusions : HOMA-AD and AR-index are reliable and valid measures for the assessment of insulin resistance in type 2 diabetic patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hamid, Ikhlas Khalid& Rashid, Nada F.& Ubayd, Bayda A.. 2013. Homestasis model assessment-adiponectin ratio and adiponectin-resistin index as markers of insulin resistance in type 2 diabetes mellitus. Journal of the Faculty of Medicine Baghdad،Vol. 55, no. 2, pp.175-178.
https://search.emarefa.net/detail/BIM-336315
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rashid, Nada F.…[et al.]. Homestasis model assessment-adiponectin ratio and adiponectin-resistin index as markers of insulin resistance in type 2 diabetes mellitus. Journal of the Faculty of Medicine Baghdad Vol. 55, no. 2 (2013), pp.175-178.
https://search.emarefa.net/detail/BIM-336315
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hamid, Ikhlas Khalid& Rashid, Nada F.& Ubayd, Bayda A.. Homestasis model assessment-adiponectin ratio and adiponectin-resistin index as markers of insulin resistance in type 2 diabetes mellitus. Journal of the Faculty of Medicine Baghdad. 2013. Vol. 55, no. 2, pp.175-178.
https://search.emarefa.net/detail/BIM-336315
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 177-178
رقم السجل
BIM-336315
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر