Breast cancer laterality among Egyptian patients and its association with treatments and survival
المؤلفون المشاركون
Ramadan, Muhammad
al-Mashad, Nahhal
Diya, Amirah
Masad, Ihab
Fakhr, Ibrahim
Zayn al-Din, Ahmad A.
المصدر
Journal of the Egyptian National Cancer Institute
العدد
المجلد 25، العدد 4 (31 ديسمبر/كانون الأول 2013)، ص ص. 199-207، 9ص.
الناشر
جامعة القاهرة المعهد القومي للأورام
تاريخ النشر
2013-12-31
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الموضوعات
الملخص EN
Background and aim : breast cancers (BCs) involve the left side (LS) more than the right side (RS).
Among the Egyptians, neither BC laterality nor its association with demographic factors, tumor locations, treatments and outcomes were previously reported.
Patients and methods: Laterality was analyzed among 5459 BCs from the Gharbiah populationbased cancer registry covering > 5 % of the Egyptian population.
Cox proportional model was used to assess the independent effect of stage, ER, and laterality on overall survival (OS).
Results : in Egypt, BCs involve LS more than RS with LS-to-RS ratio (LRR) of 1.16.
LS predominance was evident among men and women and both younger (< 45 years) and older patients.
HER2 over-expression and ductal cancers were significantly more in RSBCs while lobular cancers were significantly more in LSBCs.
There were no significant differences in localization within the breast between LSBCs and RSBCs (p = 0.51).
LS predominance was noticed across all subgroups except in patients with HER2 positive tumors (LRR = 0.63 ; p = 0.02).
OS was significantly better in stage II and ER positive tumors than stage III and ER negative tumors.
Despite OS of LSBCs being generally lower than RSBCs, this was not statistically significant.
The significant impact of stage on OS was lost in LSBCs.
Conclusions : Among Egyptian patients, the left breast is at greater risk of cancer than the right one.
Despite right-sided tumors seemed more aggressive, Left-sided ones tend to confer worse survival than right-sided tumors.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zayn al-Din, Ahmad A.& Ramadan, Muhammad& al-Mashad, Nahhal& Fakhr, Ibrahim& Diya, Amirah& Masad, Ihab. 2013. Breast cancer laterality among Egyptian patients and its association with treatments and survival. Journal of the Egyptian National Cancer Institute،Vol. 25, no. 4, pp.199-207.
https://search.emarefa.net/detail/BIM-347898
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zayn al-Din, Ahmad A.…[et al.]. Breast cancer laterality among Egyptian patients and its association with treatments and survival. Journal of the Egyptian National Cancer Institute Vol. 25, no. 4 (Dec. 2013), pp.199-207.
https://search.emarefa.net/detail/BIM-347898
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zayn al-Din, Ahmad A.& Ramadan, Muhammad& al-Mashad, Nahhal& Fakhr, Ibrahim& Diya, Amirah& Masad, Ihab. Breast cancer laterality among Egyptian patients and its association with treatments and survival. Journal of the Egyptian National Cancer Institute. 2013. Vol. 25, no. 4, pp.199-207.
https://search.emarefa.net/detail/BIM-347898
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 206-207
رقم السجل
BIM-347898
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر