Serum levels of IL-4, immunoglobulines and complements during human amoebiasis

الملخص EN

In this work ( 60 ) serum samples of patients suffered from diarrhea and infected with Entamoeba histolytica were examined to evaluate the IL – 4 concentration by ELISA method and the concentration of IgG, IgA, IgM , C3 and C4 by single radial immunodiffusion .

Recent study revealed that there was an increasing in concentration of the studied cytokine ( IL-4 ) in patients serum ( 29.

11 ) pg/ml in comparasion with control group with a highly significant differences ( p < 0.

01 ) .

Moreover , the present results showed that the mean concentration of IgG and IgA in patients with differences ( p < 0.

05 ) , while there was no significant differences in concentration of IgM between two studied groups , ( although there is an increasing in it's concentration in some patients more than the normal values ) .

The data revealed significant differences ( p < 0.

05 ) in concentration of C3 between two analyzed group .

whereas a highly significant differences ( p < 0.

01 ) in concentration of C4 was established between patients and control groups .