Synthesis, characterization, antimicrobial and diuretic study of Mg (II), Mn (II), Fe (II) and VO (II) complexes of chemotherapeutic importance
المؤلفون المشاركون
Iqbal, Sayyid Aftab
Ghosh, Suparna
Malik, Suman
Jain, Bharti
المصدر
Journal of Saudi Chemical Society
العدد
المجلد 16، العدد 2 (30 إبريل/نيسان 2012)، ص ص. 137-142، 6ص.
الناشر
تاريخ النشر
2012-04-30
دولة النشر
السعودية
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
The synthesis, characterization and diuretic activity of four new biologically active complexes of Mg(II) and VO(II) with bidentate Schiff base ligand acetazolamide–salicylaldimine (L) obtained from the inserted condensation of 5-acetamido-1,3,4-thiadiazole-2-sulphonamide (acetazolamide) with salicylaldehyde in a 1:1 molar ratio have been reported.
Using this bidentate ligand complexes of Mg(II), Mn(II), Fe(II) and VO(II) with general formula ML2 have been synthesized.
The synthesized complexes were characterized by several techniques using elemental analysis, FTIR, electronic spectra, TGA, mass, particle size analysis and molar conductance measurements.
The elemental analysis data suggest the stoichiometry to be 1:2 [M:L].
The molar conductance measurements suggest non-electrolytic nature of the complexes.
Infrared spectral data agreed with the coordination to the central metal ion through deprotonated phenolic oxygen and azomethine nitrogen atoms.
On the basis of spectral studies, octahedral geometry is suggested for Mg(II), Mn(II), Fe(II) and square pyramidal geometry is suggested for VO(II) complexes.
The pure drug, synthesized ligand and metal(II) complexes were screened for their antimicrobial activities against Eschericia coli, Bacillus subtilis, Aspergillus niger and Aspergillus flavous.
The results show that the metal complexes were more active than the ligand and pure drug against these microbial species as expected.
The ligand and its Mg(II) complexes was screened for their diuretic activity also.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ghosh, Suparna& Malik, Suman& Jain, Bharti& Iqbal, Sayyid Aftab. 2012. Synthesis, characterization, antimicrobial and diuretic study of Mg (II), Mn (II), Fe (II) and VO (II) complexes of chemotherapeutic importance. Journal of Saudi Chemical Society،Vol. 16, no. 2, pp.137-142.
https://search.emarefa.net/detail/BIM-351673
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ghosh, Suparna…[et al.]. Synthesis, characterization, antimicrobial and diuretic study of Mg (II), Mn (II), Fe (II) and VO (II) complexes of chemotherapeutic importance. Journal of Saudi Chemical Society Vol. 16, no. 2 (Apr. 2012), pp.137-142.
https://search.emarefa.net/detail/BIM-351673
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ghosh, Suparna& Malik, Suman& Jain, Bharti& Iqbal, Sayyid Aftab. Synthesis, characterization, antimicrobial and diuretic study of Mg (II), Mn (II), Fe (II) and VO (II) complexes of chemotherapeutic importance. Journal of Saudi Chemical Society. 2012. Vol. 16, no. 2, pp.137-142.
https://search.emarefa.net/detail/BIM-351673
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 142-143
رقم السجل
BIM-351673
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر