Expression of matrix metalloproteinase-2 in the extracellular matrix of osseointegrated and diseased implants
المؤلف
المصدر
Journal of Baghdad College of Dentistry
العدد
المجلد 25، العدد 3 (30 سبتمبر/أيلول 2013)، ص ص. 176-182، 7ص.
الناشر
تاريخ النشر
2013-09-30
دولة النشر
العراق
عدد الصفحات
7
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : Recently with improvement of dental implantology science, osseointegrated implants show a considerable durability, however; failures are not completely avoidable.
Matrix metalloproteinase-2 (MMP-2) expression is disturbed in many pathological conditions such as peri-implantitis and periodontitis.
This study was carried out to investigate the tissue expression of MMP-2 in the extracellular matrix of osseointegrated and diseased implants.
Subjects and methods: Gingival biopsies were collected from six patients having osseointegrated or working implants and twenty with diseased or non osseointegrated implants and (6) controls having no implants.
In situ hybridization technique was used to analyze the changes in immunoreactivity of ECM-controlling MMP-2.
Results: The findings of the present study indicate that the expression of MMP2 was significantly elevated in failed implants versus healthy implants (P < 0.01).
In addition, MMP-2 was detected in peri-implant sites with ongoing bone loss, cavitations and inflammatory reaction.
Conclusion : The in situ hybridization technique, showed clear evidence that MMP-2, which is involved in the process of osseointegration and bone remodeling, increase greatly in the presence of bone destruction, cavitations, severe inflammation and fibrous tissue formation.
The data link titanium- induced bone remodeling to changes in expressionand distribution of MMP-2.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Duboni, Ghada I.. 2013. Expression of matrix metalloproteinase-2 in the extracellular matrix of osseointegrated and diseased implants. Journal of Baghdad College of Dentistry،Vol. 25, no. 3, pp.176-182.
https://search.emarefa.net/detail/BIM-353140
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Duboni, Ghada I.. Expression of matrix metalloproteinase-2 in the extracellular matrix of osseointegrated and diseased implants. Journal of Baghdad College of Dentistry Vol. 25, no. 3 (Sep. 2013), pp.176-182.
https://search.emarefa.net/detail/BIM-353140
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Duboni, Ghada I.. Expression of matrix metalloproteinase-2 in the extracellular matrix of osseointegrated and diseased implants. Journal of Baghdad College of Dentistry. 2013. Vol. 25, no. 3, pp.176-182.
https://search.emarefa.net/detail/BIM-353140
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes appendices : p. 180-182
رقم السجل
BIM-353140
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر