Biological activity of Carica Papaya crown in Jordan
مقدم أطروحة جامعية
مشرف أطروحة جامعية
al-Khatib, Iqbal
Muhaydat, Nizar M.
الجامعة
جامعة عمان الأهلية
الكلية
كلية الصيدلة و العلوم الطبية
القسم الأكاديمي
قسم العلوم الصيدلانية
دولة الجامعة
الأردن
الدرجة العلمية
ماجستير
تاريخ الدرجة العلمية
2012
الملخص الإنجليزي
Carica papaya (Caricaceae) blown as paw paw or papaw, originally derived from die southern Mexico and Australia.
It is presently distributed over the whole tropical area.
In Jordan it is cultivated in AlGhoor.
Various parts of Carica papaya have been traditionally used as ethno medicine for a number of disorders, including psoriasis, ringworm, warts, tumors, corns and many other uses.
The goal of this study is to examine the effect of the total extract of Carica papaya leaves, seeds and fruit on the growth of various tumor cell lines in addition to antioxidant activity of leaves extract.
Papaya plant parts (leaves, seeds, ripe and unripe fruit) subjected for extraction by different polarity of solvents (chloroform, methanol and ethanol).
Furthermore, the plant extract was subjected to column chromatography and preparative TLC.
Followed by identification for compounds by various methods of chromatography (TLC, HPLC) and chemical reagent.
The biological activity were carried to estimate the antitumor activity.
The acute cytotoxic effect of the extracts on human cancer cell lines was determined using MTT assays by using human melanoma (MV3, C32), breast (MDA-MB-486, MCF7), and colorectal (SW480, HCT116).
The evaluation of antioxidant activity of leaves methanol extract was done by DPPH free radical scavenging method.
Plant extracts induced variable degrees of cytotoxicity against cancer cell lines due to their active constituents which were observed in different parts of the plant in addition to antioxidant activity 0،'leaves.
This is the first results belong to Carica papaya which cultivated in Jordan under different environmental conditions.
التخصصات الرئيسية
الموضوعات
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Kit, Samar Ahmad M.. (2012). Biological activity of Carica Papaya crown in Jordan. (Master's theses Theses and Dissertations Master). Al-Ahliyya Amman University, Jordan
https://search.emarefa.net/detail/BIM-357807
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Kit, Samar Ahmad M.. Biological activity of Carica Papaya crown in Jordan. (Master's theses Theses and Dissertations Master). Al-Ahliyya Amman University. (2012).
https://search.emarefa.net/detail/BIM-357807
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Kit, Samar Ahmad M.. (2012). Biological activity of Carica Papaya crown in Jordan. (Master's theses Theses and Dissertations Master). Al-Ahliyya Amman University, Jordan
https://search.emarefa.net/detail/BIM-357807
لغة النص
الإنجليزية
نوع البيانات
رسائل جامعية
رقم السجل
BIM-357807
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر