Amelioratory effects of vitamin E against biochemical toxicity induced by deltamethrin in male rats
المؤلفون المشاركون
al-Maghribi, Sumayyah
Taha, Hamdi A.
المصدر
Journal of the Arab Society for Medical Research
العدد
المجلد 7، العدد 2 (31 ديسمبر/كانون الأول 2012)، ص ص. 92-96، 5ص.
الناشر
تاريخ النشر
2012-12-31
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الموضوعات
الملخص EN
Deltamethrin (DLM) is a synthetic pyrethroid insecticide known for its wide toxic manifestations.
The present experiment pertains to the protective role of vitamin E (vit E) against biochemical toxicity following pesticide exposure during 30 days.
Materials and methods Male albino rats were divided into four groups of six each: Group I served as control rats (0 mg (vit E) and 0 mg DLM / kg body weight), Group II received deltamethrin (7.5mg / kg body weight).
Group III received vit E (100 mg / kg body weight).
Group IV received both deltamethrin (7.5mg / kg body weight) plus vit E (100mg / kg body weight).
Results Exposure of rats to DLM induced significant increase in the levels of hepatic markers enzymes, alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP) ; while acetylcholinesterase (AChE) was inhibited.
Significant decrease in catalase (CAT) and glutathione S-transferase (GST) enzyme activities were observed in treated rats.
Furthermore, renal markers such as urea and creatinine were increased in deltamethrin treated rats.
Additionally, serum cholesterol, triglycerides, low-density lipoprotein (LDL) and the level of high-density lipoprotein (HDL) were significantly increased and decreased, respectively.
Co-administration of vit E restored all the parameters cited above to near-normal values.
Conclusion our investigation showed that vit E acts as an effective antioxidant for DLM pesticide toxicity in reducing oxidative stress burden.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Maghribi, Sumayyah& Taha, Hamdi A.. 2012. Amelioratory effects of vitamin E against biochemical toxicity induced by deltamethrin in male rats. Journal of the Arab Society for Medical Research،Vol. 7, no. 2, pp.92-96.
https://search.emarefa.net/detail/BIM-359090
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Maghribi, Sumayyah& Taha, Hamdi A.. Amelioratory effects of vitamin E against biochemical toxicity induced by deltamethrin in male rats. Journal of the Arab Society for Medical Research Vol. 7, no. 2 (2012), pp.92-96.
https://search.emarefa.net/detail/BIM-359090
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Maghribi, Sumayyah& Taha, Hamdi A.. Amelioratory effects of vitamin E against biochemical toxicity induced by deltamethrin in male rats. Journal of the Arab Society for Medical Research. 2012. Vol. 7, no. 2, pp.92-96.
https://search.emarefa.net/detail/BIM-359090
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 95-96
رقم السجل
BIM-359090
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر