Improvement of lipid profile and antioxidant of hypercholesterolemic albino rats by polysaccharides extracted from the green alga Ulva lactuca Linnaeus
المؤلفون المشاركون
Hasan, Sharif
Abd al-Tawwab, Sana
Hittah, Muna
Mahmud, Basant
المصدر
Saudi Journal of Biological Sciences
العدد
المجلد 18، العدد 4 (31 ديسمبر/كانون الأول 2011)، ص ص. 333-340، 8ص.
الناشر
تاريخ النشر
2011-12-31
دولة النشر
السعودية
عدد الصفحات
8
التخصصات الرئيسية
الموضوعات
الملخص EN
Sulfated polysaccharides from Ulva lactuca were extracted in hot water and precipitated by ethanol then orally gavaged to rats fed on a hypercholesterolemic diet for 21 days to evaluate the antihypercholesterolemic and antioxidant actions.
Atorvastatine Ca (Lipitor) was used as a reference drug.
The intragastric administration of U.
lactuca extract to hypercholesterolemic rats caused significant decrease of serum total lipids, triglycerides, total cholesterol, LDL-cholesterol and vLDL-cholesterol levels.
Whereas, HDL-cholesterol concentration was markedly increased by 180 %.
Aqueous extract showed a significant ameliorative action on elevated atherogenic index, creatine kinase and lactate dehydrogenase activities of hypercholesterolemic group.
Furthermore, serum activities of transaminases and alkaline phosphatase were also improved.
High fat diet intake caused a highly significantly elevated serum urea, creatinine concentration.
These effects were reversed by oral administration of U.
lactuca extract.
Sulfates polysaccharides extract of U.
lactuca ameliorate hepatic enzymatic (catalase, glutathione peroxidase and superoxide dismutase), nonenzymatic (reduced glutathione & total thiol) antioxidant defenses and thiobarbituric acid reactive substances.
In conclusion, the tested U.
lactuca polysaccharides extract has potent hypocholesterolemic and antioxidant effects in experimentally-induced hypercholesterolemic animal model.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hasan, Sharif& Abd al-Tawwab, Sana& Hittah, Muna& Mahmud, Basant. 2011. Improvement of lipid profile and antioxidant of hypercholesterolemic albino rats by polysaccharides extracted from the green alga Ulva lactuca Linnaeus. Saudi Journal of Biological Sciences،Vol. 18, no. 4, pp.333-340.
https://search.emarefa.net/detail/BIM-364541
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hasan, Sharif…[et al.]. Improvement of lipid profile and antioxidant of hypercholesterolemic albino rats by polysaccharides extracted from the green alga Ulva lactuca Linnaeus. Saudi Journal of Biological Sciences Vol. 18, no. 4 (2011), pp.333-340.
https://search.emarefa.net/detail/BIM-364541
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hasan, Sharif& Abd al-Tawwab, Sana& Hittah, Muna& Mahmud, Basant. Improvement of lipid profile and antioxidant of hypercholesterolemic albino rats by polysaccharides extracted from the green alga Ulva lactuca Linnaeus. Saudi Journal of Biological Sciences. 2011. Vol. 18, no. 4, pp.333-340.
https://search.emarefa.net/detail/BIM-364541
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 339-340
رقم السجل
BIM-364541
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر