Parathyroid hormone and bone minerals in Sudanese patients with end-stage renal disease : pre and post hemodialysis
مقدم أطروحة جامعية
al-Amin, Abd al-Salam al-Ubayd Muhammad
مشرف أطروحة جامعية
al-Amin, Abd al-Aziz
Izz al-Din, Umar Musa
الجامعة
جامعة أم درمان الإسلامية
الكلية
كلية المختبرات الطبية
القسم الأكاديمي
قسم الكيمياء السريرية
دولة الجامعة
السودان
الدرجة العلمية
دكتوراه
تاريخ الدرجة العلمية
2011
الملخص الإنجليزي
-Background: End-stage renal disease (ESRD) is associated with changes in bone minerals and parathyroid hormone (PTH). Objective: The study aimed to determine serum levels of parathyroid hormone, calcium and phosphate in patients with ESRD and its relation to hemodialysis. Methods: A cross sectional case-control study during the period of study at three hemodialysis units in Omdurman.
One hundred patients with ESRD on regular hemodialysis participated in the study.
Fifty healthy subjects acted as controls.
History and physical findings were documented and blood samples collected for analysis of PTH, bone minerals and other tests. Results: Out of 100 patients, 69 were males and 31 were females.
Age ranged from 15 to 80 years (mean was 47.5 years ± 12.5).
The study found high serum levels of PTH in the patients before dialysis (119.7 pg/ml) compared to controls (31.0 pg/ml), and significant decreased of serum PTH levels after dialysis (61.3 pg/ml).
Serum calcium concentration was low in the patients before dialysis compared to controls (6.8 mg/dl vs.
9.3 mg/dl) and it increased significantly after hemodialysis (7.8 mg/dl).
In contrast the serum phosphate concentration before dialysis was high in patients compared to controls (5.45mg/dl vs.
3.59 mg/dl).
However, it dropped to 3.8 mg/dl after hemodialysis.
The study found no significant correlation between PTH levels and age, cause of ESRD, duration of disease, and frequency of hemodialysis sessions.
However, there was gender difference on PTH levels being lower in males compared to that in females
التخصصات الرئيسية
الموضوعات
عدد الصفحات
198
قائمة المحتويات
Table of contents.
Abstract.
Chapter One : Introduction and objectives.
Chapter Two : Literature review.
Chapter Three : Subjects and methods.
Chapter Four : Results.
Chapter Five : Discussion and conclusion.
References.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Amin, Abd al-Salam al-Ubayd Muhammad. (2011). Parathyroid hormone and bone minerals in Sudanese patients with end-stage renal disease : pre and post hemodialysis. (Doctoral dissertations Theses and Dissertations Master). Omdurman Islamic University, Sudan
https://search.emarefa.net/detail/BIM-364710
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Amin, Abd al-Salam al-Ubayd Muhammad. Parathyroid hormone and bone minerals in Sudanese patients with end-stage renal disease : pre and post hemodialysis. (Doctoral dissertations Theses and Dissertations Master). Omdurman Islamic University. (2011).
https://search.emarefa.net/detail/BIM-364710
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Amin, Abd al-Salam al-Ubayd Muhammad. (2011). Parathyroid hormone and bone minerals in Sudanese patients with end-stage renal disease : pre and post hemodialysis. (Doctoral dissertations Theses and Dissertations Master). Omdurman Islamic University, Sudan
https://search.emarefa.net/detail/BIM-364710
لغة النص
الإنجليزية
نوع البيانات
رسائل جامعية
رقم السجل
BIM-364710
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
