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Complement and hyper acute rejection
المؤلف
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 20، العدد 3 (30 يونيو/حزيران 2009)، ص ص. 362-369، 8ص.
الناشر
تاريخ النشر
2009-06-30
دولة النشر
السعودية
عدد الصفحات
8
التخصصات الرئيسية
الموضوعات
الملخص EN
Organ transplantation has been a major development in clinical medicine but its success has been marred by the immune system's capacity to respond to "non-self" cells and tissues.
A full molecular understanding of this mechanism and the myriad triggers for immune rejection is yet to be elucidated.
Consequently, immunosuppressive drugs remain the mainstay of post-transplant management; however, these interventions have side effects such as increased incidence of cancer, post-transplant lymphoproliferative disorders, susceptibility to infection if not managed appropriately and the inconvenience to the patient of lifelong treatment.
Novel therapeutic approaches based on molecular understanding of immunological processes are thus needed in this field.
The notion that factors influencing successful transplants might be of use as therapeutic approaches is both scientifically and medically appealing.
Recent developments in the understanding of successful transplants are expected to provide new opportunities for safer transplantation.
This article reviews the present understanding of the molecular basis of rejection and the role of complement in this process as well as the possibility of generating "intelligent" therapy that better target crucial components of hyperacute rejections.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Rabiah, Muhammad W. O.. 2009. Complement and hyper acute rejection. Saudi Journal of Kidney Diseases and Transplantation،Vol. 20, no. 3, pp.362-369.
https://search.emarefa.net/detail/BIM-36637
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Rabiah, Muhammad W. O.. Complement and hyper acute rejection. Saudi Journal of Kidney Diseases and Transplantation Vol. 20, no. 3 (Sep. 2009), pp.362-369.
https://search.emarefa.net/detail/BIM-36637
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Rabiah, Muhammad W. O.. Complement and hyper acute rejection. Saudi Journal of Kidney Diseases and Transplantation. 2009. Vol. 20, no. 3, pp.362-369.
https://search.emarefa.net/detail/BIM-36637
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 367-369
رقم السجل
BIM-36637
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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