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Comparison of 24-jour urinary protein and -to-creatinine ratio in the assessment of proteinuria
المؤلفون المشاركون
Wahbi, Ayman M.
Uways, Muhammad H.
al-Sharif, Muhammad E.
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 20، العدد 3 (30 يونيو/حزيران 2009)، ص ص. 443-447، 5ص.
الناشر
تاريخ النشر
2009-06-30
دولة النشر
السعودية
عدد الصفحات
5
التخصصات الرئيسية
الموضوعات
- الامتحانات
- الكلى
- الأمراض
- علم الأمراض
- البروتين البولي
- تحليل البول
- الأردن
- السيميائية
- الكرياتينين
- الكيمياء السريرية
الملخص EN
To determine the correlation between protein-to-creatinine ratio (PCR) and 24-hour urinary protein (UP), we measured proteinuria in 68 patients attending the nephrology clinic at Jordan University Hospital by 24-hour urine protein excretion and protein-to-creatinine ratio.
The cutoff values for spot urine protein-to-creatinine ratio in predicting 24-hour protein "threshold" excretion of 0.5, 1.0 and 3.5 g / day were determined using receiver operating characteristic curves.
A very good correlation (r= 0.832, P< 0.0001) was found between spot urine protein-to-creatinine ratio and 24-hour urine protein excretion.
Bland-Altman plot showed the two tests had reasonable limits of agreement at low level of protein excretion but the limits became wider as the protein excretion increased.
For protein excretion < 2.0 g / day, the limits of agreement of spot urine (PCR) and (UP) were +1.48 and -1.2 g / day.
The spot urine protein-to-creatinine ratios of 0.72 (sensitivity 0.97; specificity 1.0), 1.2 (0.97; 0.89) and 3.23 (1.0; 0.86) mg / mg reliably predicted 24-hour urine total protein equivalent "thresholds" of 0.5, 1.0 and 3.5 g / day, respectively.
We conclude that the protein-to-creatinine ratio in spot urine specimens is an accurate, convenient, and reliable method to estimate the protein excretion in urine.
However, the protein-to-creatinine ratio will likely be within clinically acceptable limits only when proteinuria is at reasonably low levels.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wahbi, Ayman M.& Uways, Muhammad H.& al-Sharif, Muhammad E.. 2009. Comparison of 24-jour urinary protein and -to-creatinine ratio in the assessment of proteinuria. Saudi Journal of Kidney Diseases and Transplantation،Vol. 20, no. 3, pp.443-447.
https://search.emarefa.net/detail/BIM-36823
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wahbi, Ayman M.…[et al.]. Comparison of 24-jour urinary protein and -to-creatinine ratio in the assessment of proteinuria. Saudi Journal of Kidney Diseases and Transplantation Vol. 20, no. 3 (Sep. 2009), pp.443-447.
https://search.emarefa.net/detail/BIM-36823
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wahbi, Ayman M.& Uways, Muhammad H.& al-Sharif, Muhammad E.. Comparison of 24-jour urinary protein and -to-creatinine ratio in the assessment of proteinuria. Saudi Journal of Kidney Diseases and Transplantation. 2009. Vol. 20, no. 3, pp.443-447.
https://search.emarefa.net/detail/BIM-36823
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 446-447
رقم السجل
BIM-36823
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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