Electrophysiological study of peripheral nerves in children with acute lymphoblastic leukemia
المؤلفون المشاركون
Umar, Karim A.
Hisab, Huda
Imam, Muhammad H.
Abd al-Ghani, Hiyam M.
المصدر
Egyptian Rheumatology and Rehabilitation
العدد
المجلد 40، العدد 2 (30 يونيو/حزيران 2013)، ص ص. 63-69، 7ص.
الناشر
الجمعية المصرية للروماتيزم و التأهيل
تاريخ النشر
2013-06-30
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الموضوعات
الملخص EN
Background Acute lymphoblastic leukemia (ALL) is a malignant disorder of lymphoid progenitor cells affecting both children and adults.
Chemotherapy-induced peripheral neurotoxicity is an important side effect of several chemotherapeutic agents.
Objectives The aim of this study was to detect the presence and types of peripheral neuropathy (PN) in newly diagnosed children with ALL, before and after the phase of induction of remission.
Methodology A total of 24 children newly diagnosed with ALL were enrolled into the study (group I).
They were subjected to clinical and electrodiagnostic assessments to examine the integrity of the peripheral nervous system before and after receiving chemotherapeutic agents.
Ten apparently healthy children served as controls (group II).
Results Electrodiagnostic assessment revealed that 16 children (67%) had no documented PN, whereas eight (33%) had PN.
Of these eight children, two (8.3%) were proven to have chemotherapy-induced PN, four (16.6%) had subclinical chemotherapy-induced PN, and two (8.3%) had subclinical PN due to ALL.
Of the eight children with PN, five (62.5%) had an axonal pattern, one (12.5%) had a demyelinating pattern, and two (25%) had a mixed axonal demyelinating pattern of affection.
In general, the affection of peripheral motor nerves was greater compared with sensory nerve affection.
Conclusion Chemotherapeutic agents used in the treatment of ALL (phase I: induction of remission) proved to have neurotoxic effects on peripheral nerves.
In most children, the PN was subclinical.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ibrahim, Ibrahim K.& Hisab, Huda& Imam, Muhammad H.& Abd al-Ghani, Hiyam M.& Umar, Karim A.. 2013. Electrophysiological study of peripheral nerves in children with acute lymphoblastic leukemia. Egyptian Rheumatology and Rehabilitation،Vol. 40, no. 2, pp.63-69.
https://search.emarefa.net/detail/BIM-380907
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hisab, Huda…[et al.]. Electrophysiological study of peripheral nerves in children with acute lymphoblastic leukemia. Egyptian Rheumatology and Rehabilitation Vol. 40, no. 2 (Apr. / Jun. 2013), pp.63-69.
https://search.emarefa.net/detail/BIM-380907
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ibrahim, Ibrahim K.& Hisab, Huda& Imam, Muhammad H.& Abd al-Ghani, Hiyam M.& Umar, Karim A.. Electrophysiological study of peripheral nerves in children with acute lymphoblastic leukemia. Egyptian Rheumatology and Rehabilitation. 2013. Vol. 40, no. 2, pp.63-69.
https://search.emarefa.net/detail/BIM-380907
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 69
رقم السجل
BIM-380907
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر