Antibiotic susceptibility patterns and molecular epidemiology of metallo-β-lactamase producing pseudomonas aeruginosa strains isolated from burn patients
المؤلفون المشاركون
Giammanco, Giovanni M.
Japoni, Aziz
Anvarinejad, Mujtaba
Farshad, Shohreh
Rafaatpour, Nur al-Din
Alipour, Ibrahim
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 16، العدد 5 (31 مايو/أيار 2014)، ص ص. 1-6، 6ص.
الناشر
تاريخ النشر
2014-05-31
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : Failure in the treatment of burn patients infected with Pseudomonas aeruginosa could happen as a result of the acquisition of antibiotic resistance, including carbapenems.
Objectives : The aim of the present study was to investigate the phenotypic and genotypic characteristics of the Pseudomonas aeruginosa strains, isolated from burn patients.
Patients and Methods : During a 12 month period, in this cross-sectional study, two hundred seventy strains of Pseudomonas aeruginosa were isolated from the burn patients in Ghotbeddin Burn Hospital, Shiraz, Iran.
Screening for the carbapenem resistance in the isolates was carried out by the E test method.
Sensitivity patterns of metallo-β-lactamase (MβLs) producing strains of pseudomonas to eleven antibiotics were determined by the mentioned method.
The epidemiological associations of these strains were determined by Pulsed-field gel electrophoresis (PFGE).
Results : Of the 270 strains, 60 (22.2 %) were resistant to imipenem and meropenem, classified as MβLs producing.
MβLs producing strains of pseudomonas were completely resistant to five tested antibiotics while their sensitivities to the three most effective antibiotics including ceftazidime, amikacin and ciprofloxacin were 23.4 %, 6.7 % and 1.7 %, respectively.
In PFGE, 37 patterns from the genome of Pseudomonas aeruginosa were observed.
Majority of the strains (43 ; 71.6 %) exhibited more than 80 % similarity, based on the drawn dendrogram.
Conclusions : According to the results, none of the tested antibiotics is safe to prescribe.
As PFGE revealed, a limited number of Pseudomonas aeruginosa types are predominant in the hospitals which infect the burn patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Japoni, Aziz& Anvarinejad, Mujtaba& Farshad, Shohreh& Giammanco, Giovanni M.& Rafaatpour, Nur al-Din& Alipour, Ibrahim. 2014. Antibiotic susceptibility patterns and molecular epidemiology of metallo-β-lactamase producing pseudomonas aeruginosa strains isolated from burn patients. Iranian Red Crescent Medical Journal،Vol. 16, no. 5, pp.1-6.
https://search.emarefa.net/detail/BIM-385690
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Japoni, Aziz…[et al.]. Antibiotic susceptibility patterns and molecular epidemiology of metallo-β-lactamase producing pseudomonas aeruginosa strains isolated from burn patients. Iranian Red Crescent Medical Journal Vol. 16, no. 5 (May. 2014), pp.1-6.
https://search.emarefa.net/detail/BIM-385690
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Japoni, Aziz& Anvarinejad, Mujtaba& Farshad, Shohreh& Giammanco, Giovanni M.& Rafaatpour, Nur al-Din& Alipour, Ibrahim. Antibiotic susceptibility patterns and molecular epidemiology of metallo-β-lactamase producing pseudomonas aeruginosa strains isolated from burn patients. Iranian Red Crescent Medical Journal. 2014. Vol. 16, no. 5, pp.1-6.
https://search.emarefa.net/detail/BIM-385690
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 5-6
رقم السجل
BIM-385690
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر