Study of growth hormone and insulin- likegrowth factor-1 in type 1 diabetes mellituswith diabetic nephropathy
المصدر
Egyptian Journal of Applied Endocrinology
العدد
المجلد 20، العدد 1-2 (31 يوليو/تموز 2002)، ص ص. 113-134، 22ص.
الناشر
الجمعية المصرية للغدد الصماء التطبيقية
تاريخ النشر
2002-07-31
دولة النشر
مصر
عدد الصفحات
22
التخصصات الرئيسية
الملخص EN
BACKGROUND : Patients with type 1 diabetes exhibit abnormalities of the growth hormone (GH), Insulin-like growth factor (IGF) and Insulin-like growth factor binding protein-3 (IGFBP-3) axis, including GH hpyersecretion, reduced circulating levels of IGF-I and IGFBP-3.
These changes may contribute to the pathogenesis of diabetic-specific complications, including diabetic neuropathy, neophropathy and retinopathy.
Diabetic nephropathy is one of the most common secondary complications of diabetes mellitus.
GH and IGF-I have suggested to be involved in diabetic nephropathy, at least in the early renal hypertrophy/hyper function period.
• OBJECTIVE : The present work aimed to study the possible relationship of these hormonal factors (GH, IGF-I and IGFBP-3) to diabetic nephropathy.
• STUDY Design : We conducted our study on 50 subjects, 30 type I diabetic patients and 20 healthy persons.
The 30 diabetic patients were 27 patients with complications [22 with diabetic nephropathy, (12 patients had diabetic nephropathy with normal albuminuria, 9 patients had microalbuminuria and 1 patient had diabetic nephropathy with macroalbuminuria) and 5 complicated diabetic patients wihtout nephropathy] and 3 diabetic patients had no complications.
Our patients age ranged from 15 to 35 years.
Patients with secondary form of diabetes, chronic liver diasease, chronic kidney diasease, hypertension and short stature were excluded.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jamal al-Din, Suhayr Muhammad& Shilbaya, Salah& Shuayb, Nihad& al-Sayyid, Hadiyah& Subhi, Munir& Abd al-Munim, Tahany…[et al.]. 2002. Study of growth hormone and insulin- likegrowth factor-1 in type 1 diabetes mellituswith diabetic nephropathy. Egyptian Journal of Applied Endocrinology،Vol. 20, no. 1-2, pp.113-134.
https://search.emarefa.net/detail/BIM-393598
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shilbaya, Salah…[et al.]. Study of growth hormone and insulin- likegrowth factor-1 in type 1 diabetes mellituswith diabetic nephropathy. Egyptian Journal of Applied Endocrinology Vol. 20, no. 1-2 (Jan. / Jul. 2002), pp.113-134.
https://search.emarefa.net/detail/BIM-393598
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jamal al-Din, Suhayr Muhammad& Shilbaya, Salah& Shuayb, Nihad& al-Sayyid, Hadiyah& Subhi, Munir& Abd al-Munim, Tahany…[et al.]. Study of growth hormone and insulin- likegrowth factor-1 in type 1 diabetes mellituswith diabetic nephropathy. Egyptian Journal of Applied Endocrinology. 2002. Vol. 20, no. 1-2, pp.113-134.
https://search.emarefa.net/detail/BIM-393598
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes appendices.
رقم السجل
BIM-393598
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر