Synthesis and antibacterial evaluation of some n-amino acid-3-phthalimidine amino acid esters

الملخص EN

Some new amino acid derivatives were prepared from the reaction of amino acids esters (glycine, tyrosine and cystine) with 2-thioxo phthaloyl of the following amino acids (leucine, valine, glycine and alanine), The reaction products were tested against six types of bacteria.

The results indicated that N-valyl-3- phthalimidine ethyl tyrosinate and N-anyl-3- phthalimidine ethyl cystinate showed remarkable activity against Pseudomonas araginosa.

The synthesized compounds were characterized by using elemental analysis.

IR spectral methods and their melting points.-