Synthesis and antibacterial evaluation of some n-amino acid-3-phthalimidine amino acid esters

Other Title(s)

تحضير بعض-N حامض أميني-3-فثاليميدين استر حامض أميني و دراسة فعالياتها البايولوجية

Joint Authors

al-Ujayli, Muhammad Salman
Bashir, Huda Ahmad
Sulayman, Siba Muayyad

Source

Teachers College Researcher Journal

Issue

Vol. 1, Issue 1 (31 Mar. 2003), pp.244-252, 9 p.

Publisher

University of Mosul Teachers College

Publication Date

2003-03-31

Country of Publication

Iraq

No. of Pages

9

Main Subjects

Chemistry

Topics

Abstract AR

تـم تحضـیر مشـتقات جدیـدة للأحماض الأمینیـة مـن تفاعـل أسترات الأحمـاض الأمینیـة (كلایسـین – تایروسـین – سایسـتین) مـع 2- ثایواوكوفثالویـل للأحمـاض الأمینیـة (لیوسـین و فـالین و كلایسین و الانین) .و تم اختبار نواتج التفاعل ضد سـتة أنـواع مـن البكتریـا و قـد أظهـر المركبـات N- فالیـل - 3- فثالیمیـدین اثیــل سايستنين و N- فاليـل -3- فثالیمیــدین اثیــل تایروسـینیو فعالیــة ضــد بكتریا بسیدوموناس اراجینوسا، و قد شخصت المركبات الناتجـة بالتحلیـل الـدقیق للعناصـر و طیـف الأشعة تحت الحمراء و درجات الانصهار .

Abstract EN

Some new amino acid derivatives were prepared from the reaction of amino acids esters (glycine, tyrosine and cystine) with 2-thioxo phthaloyl of the following amino acids (leucine, valine, glycine and alanine), The reaction products were tested against six types of bacteria.

The results indicated that N-valyl-3- phthalimidine ethyl tyrosinate and N-anyl-3- phthalimidine ethyl cystinate showed remarkable activity against Pseudomonas araginosa.

The synthesized compounds were characterized by using elemental analysis.

IR spectral methods and their melting points.-

American Psychological Association (APA)

al-Ujayli, Muhammad Salman& Bashir, Huda Ahmad& Sulayman, Siba Muayyad. 2003. Synthesis and antibacterial evaluation of some n-amino acid-3-phthalimidine amino acid esters. Teachers College Researcher Journal،Vol. 1, no. 1, pp.244-252.
https://search.emarefa.net/detail/BIM-412954

Modern Language Association (MLA)

al-Ujayli, Muhammad Salman…[et al.]. Synthesis and antibacterial evaluation of some n-amino acid-3-phthalimidine amino acid esters. Teachers College Researcher Journal Vol. 1, no. 1 (2003), pp.244-252.
https://search.emarefa.net/detail/BIM-412954

American Medical Association (AMA)

al-Ujayli, Muhammad Salman& Bashir, Huda Ahmad& Sulayman, Siba Muayyad. Synthesis and antibacterial evaluation of some n-amino acid-3-phthalimidine amino acid esters. Teachers College Researcher Journal. 2003. Vol. 1, no. 1, pp.244-252.
https://search.emarefa.net/detail/BIM-412954

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 251-252

Record ID

BIM-412954