Clinical biomarkers in sickle cell disease

المؤلفون المشاركون

Kamal, Muhammad A.
Mushtaq, Gohar
Damanhuri, Ghazi A.
Jar Allah, Jumanah
Maruf, Sami
Hindawi, S. I.

المصدر

Saudi Journal of Biological Sciences

العدد

المجلد 22، العدد 1 (31 مارس/آذار 2015)، ص ص. 24-31، 8ص.

الناشر

الجمعية السعودية لعلوم الحياة

تاريخ النشر

2015-03-31

دولة النشر

السعودية

عدد الصفحات

8

التخصصات الرئيسية

الطب البشري

الموضوعات

الملخص EN

Sickle cell disease (SCD) is a hereditary blood disorder caused by a single gene.

Various blood and urine biomarkers have been identified in SCD which are associated with laboratory and medical history.

Biomarkers have been proven helpful in identifying different interconnected disease-causing mechanisms of SCD, including hypercoagulability, hemolysis, inflammation, oxidative stress, vasculopathy, reperfusion injury and reduced vasodilatory responses in endothelium, to name just a few.

However, there exists a need to establish a panel of validated blood and urine biomarkers in SCD.

This paper reviews the current contribution of biochemical markers associated with clinical manifestation and identification of sub-phenotypes in SCD.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Damanhuri, Ghazi A.& Jar Allah, Jumanah& Maruf, Sami& Hindawi, S. I.& Mushtaq, Gohar& Kamal, Muhammad A.. 2015. Clinical biomarkers in sickle cell disease. Saudi Journal of Biological Sciences،Vol. 22, no. 1, pp.24-31.
https://search.emarefa.net/detail/BIM-437397

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Damanhuri, Ghazi A.…[et al.]. Clinical biomarkers in sickle cell disease. Saudi Journal of Biological Sciences Vol. 22, no. 1 (2015), pp.24-31.
https://search.emarefa.net/detail/BIM-437397

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Damanhuri, Ghazi A.& Jar Allah, Jumanah& Maruf, Sami& Hindawi, S. I.& Mushtaq, Gohar& Kamal, Muhammad A.. Clinical biomarkers in sickle cell disease. Saudi Journal of Biological Sciences. 2015. Vol. 22, no. 1, pp.24-31.
https://search.emarefa.net/detail/BIM-437397

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references : p. 30-31

رقم السجل

BIM-437397