Characterization of the Lateral Distribution of Fluorescent Lipid in Binary-Constituent Lipid Monolayers by Principal Component Analysis
المؤلفون المشاركون
Brown, Rhoderick E.
Brockman, Howard L.
Zhai, Xiuhong
Molotkovsky, Julian G.
Sugár, István P.
Boldyrev, Ivan A.
المصدر
International Journal of Biomedical Imaging
العدد
المجلد 2010، العدد 2010 (31 ديسمبر/كانون الأول 2010)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2010-04-20
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Lipid lateral organization in binary-constituent monolayers consisting of fluorescent and nonfluorescent lipids has been investigated by acquiring multiple emission spectra during measurement of each force-area isotherm.
The emission spectra reflect BODIPY-labeled lipid surface concentration and lateral mixing with different nonfluorescent lipid species.
Using principal component analysis (PCA) each spectrum could be approximated as the linear combination of only two principal vectors.
One point on a plane could be associated with each spectrum, where the coordinates of the point are the coefficients of the linear combination.
Points belonging to the same lipid constituents and experimental conditions form a curve on the plane, where each point belongs to a different mole fraction.
The location and shape of the curve reflects the lateral organization of the fluorescent lipid mixed with a specific nonfluorescent lipid.
The method provides massive data compression that preserves and emphasizes key information pertaining to lipid distribution in different lipid monolayer phases.
Collectively, the capacity of PCA for handling large spectral data sets, the nanoscale resolution afforded by the fluorescence signal, and the inherent versatility of monolayers for characterization of lipid lateral interactions enable significantly enhanced resolution of lipid lateral organizational changes induced by different lipid compositions.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sugár, István P.& Zhai, Xiuhong& Boldyrev, Ivan A.& Molotkovsky, Julian G.& Brockman, Howard L.& Brown, Rhoderick E.. 2010. Characterization of the Lateral Distribution of Fluorescent Lipid in Binary-Constituent Lipid Monolayers by Principal Component Analysis. International Journal of Biomedical Imaging،Vol. 2010, no. 2010, pp.1-9.
https://search.emarefa.net/detail/BIM-447650
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sugár, István P.…[et al.]. Characterization of the Lateral Distribution of Fluorescent Lipid in Binary-Constituent Lipid Monolayers by Principal Component Analysis. International Journal of Biomedical Imaging No. 2010 (2010), pp.1-9.
https://search.emarefa.net/detail/BIM-447650
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sugár, István P.& Zhai, Xiuhong& Boldyrev, Ivan A.& Molotkovsky, Julian G.& Brockman, Howard L.& Brown, Rhoderick E.. Characterization of the Lateral Distribution of Fluorescent Lipid in Binary-Constituent Lipid Monolayers by Principal Component Analysis. International Journal of Biomedical Imaging. 2010. Vol. 2010, no. 2010, pp.1-9.
https://search.emarefa.net/detail/BIM-447650
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-447650
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر