A Review of Bioactive Release from Nerve Conduits as a Neurotherapeutic Strategy for Neuronal Growth in Peripheral Nerve Injury
المؤلفون المشاركون
du Toit, Lisa C.
Pillay, Viness
Ramburrun, Poornima
Choonara, Yahya E.
Kumar, Pradeep
Bijukumar, Divya
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-19، 19ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-07-21
دولة النشر
مصر
عدد الصفحات
19
التخصصات الرئيسية
الملخص EN
Peripheral nerve regeneration strategies employ the use of polymeric engineered nerve conduits encompassed with components of a delivery system.
This allows for the controlled and sustained release of neurotrophic growth factors for the enhancement of the innate regenerative capacity of the injured nerves.
This review article focuses on the delivery of neurotrophic factors (NTFs) and the importance of the parameters that control release kinetics in the delivery of optimal quantities of NTFs for improved therapeutic effect and prevention of dose dumping.
Studies utilizing various controlled-release strategies, in attempt to obtain ideal release kinetics, have been reviewed in this paper.
Release strategies discussed include affinity-based models, crosslinking techniques, and layer-by-layer technologies.
Currently available synthetic hollow nerve conduits, an alternative to the nerve autografts, have proven to be successful in the bridging and regeneration of primarily the short transected nerve gaps in several patient cases.
However, current research emphasizes on the development of more advanced nerve conduits able to simulate the effectiveness of the autograft which includes, in particular, the ability to deliver growth factors.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ramburrun, Poornima& Kumar, Pradeep& Choonara, Yahya E.& Bijukumar, Divya& du Toit, Lisa C.& Pillay, Viness. 2014. A Review of Bioactive Release from Nerve Conduits as a Neurotherapeutic Strategy for Neuronal Growth in Peripheral Nerve Injury. BioMed Research International،Vol. 2014, no. 2014, pp.1-19.
https://search.emarefa.net/detail/BIM-448247
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ramburrun, Poornima…[et al.]. A Review of Bioactive Release from Nerve Conduits as a Neurotherapeutic Strategy for Neuronal Growth in Peripheral Nerve Injury. BioMed Research International No. 2014 (2014), pp.1-19.
https://search.emarefa.net/detail/BIM-448247
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ramburrun, Poornima& Kumar, Pradeep& Choonara, Yahya E.& Bijukumar, Divya& du Toit, Lisa C.& Pillay, Viness. A Review of Bioactive Release from Nerve Conduits as a Neurotherapeutic Strategy for Neuronal Growth in Peripheral Nerve Injury. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-19.
https://search.emarefa.net/detail/BIM-448247
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-448247
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر