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Semecarpus anacardium (Bhallataka) Alters the Glucose Metabolism and Energy Production in Diabetic Rats
المؤلفون المشاركون
Palanivelu, Shanthi
Panchanadham, Sachdanandam
Aseervatham, Jaya
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2010-09-08
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Glucose produced by gluconeogenesis and glycogenolysis plays an important role in aggravating hyperglycemia in diabetes, and altered mitochondrial function is associated with impaired energy production.
The present study focuses on the effect of Semecarpus anacardium on carbohydrate metabolism and energy production in diabetic rats.
Diabetes was induced by the administration of Streptozotocin at a dose of 50 mg/kg.b.wt.
Three days after the induction, Semecarpus anacardium at a dose of 300 mg/kg.b.wt was administered for 21 days.
After the experimental duration, the activities of the enzymes involved in Glycolysis, TCA cycle, gluconeogenesis, and glycogen were assayed in the liver and kidney of the experimental animals.
In addition, to the complexes the protein expression of AKT and PI3K were assayed.
The levels of the enzymes involved in Glycolysis and TCA cycle increased, while that of gluconeogensis decreased.
The activities of the mitochondrial complexes were also favorably modulated.
The expressions of PI3K and AKT also increased in the skeletal muscle.
These effects may be attributed to the hypoglycemic and the antioxidative activity of Semecarpus anacardium.
The results of the study revealed that Semecarpus anacardium was able to restore the altered activities of the enzymes involved in carbohydrate metabolism and energy production.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Aseervatham, Jaya& Palanivelu, Shanthi& Panchanadham, Sachdanandam. 2010. Semecarpus anacardium (Bhallataka) Alters the Glucose Metabolism and Energy Production in Diabetic Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-449169
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Aseervatham, Jaya…[et al.]. Semecarpus anacardium (Bhallataka) Alters the Glucose Metabolism and Energy Production in Diabetic Rats. Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-449169
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Aseervatham, Jaya& Palanivelu, Shanthi& Panchanadham, Sachdanandam. Semecarpus anacardium (Bhallataka) Alters the Glucose Metabolism and Energy Production in Diabetic Rats. Evidence-Based Complementary and Alternative Medicine. 2010. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-449169
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-449169
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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