Biomarkers for Gastroesophageal Reflux in Respiratory Diseases
المؤلفون المشاركون
Ólafsson, Ísleifur
Emilsson, Össur Ingi
Gíslason, Þórarinn
Olin, Anna-Carin
Janson, Christer
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-04-09
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Gastroesophageal reflux (GER) is commonly associated with respiratory symptoms, either through a vagal bronchoconstrictive reflex or through microaspiration of gastric contents.
No diagnostic test is available, however, to diagnose when respiratory illnesses are caused by GER and when not, but research in this field has been moving forward.
Various biomarkers in different types of biosamples have been studied in this context.
The aim of this review is to summarize the present knowledge in this field.
GER patients with respiratory diseases seem to have a different biochemical profile from similar patients without GER.
Inflammatory biomarkers differ in asthmatics based on GER status, tachykinins are elevated in patients with GER-related cough, and bile acids are elevated in lung transplant patients with GER.
However, studies on these biomarkers are often limited by their small size, methods of analysis, and case selections.
The two pathogenesis mechanisms are associated with different respiratory illnesses and biochemical profiles.
A reliable test to identify GER-induced respiratory disorders needs to be developed.
Bronchoalveolar lavage is too invasive to be of use in most patients.
Exhaled breath condensate samples need further evaluation and standardization.
The newly developed particles in exhaled air measurements remain to be studied further.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Emilsson, Össur Ingi& Gíslason, Þórarinn& Olin, Anna-Carin& Janson, Christer& Ólafsson, Ísleifur. 2013. Biomarkers for Gastroesophageal Reflux in Respiratory Diseases. Gastroenterology Research and Practice،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-449568
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Emilsson, Össur Ingi…[et al.]. Biomarkers for Gastroesophageal Reflux in Respiratory Diseases. Gastroenterology Research and Practice No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-449568
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Emilsson, Össur Ingi& Gíslason, Þórarinn& Olin, Anna-Carin& Janson, Christer& Ólafsson, Ísleifur. Biomarkers for Gastroesophageal Reflux in Respiratory Diseases. Gastroenterology Research and Practice. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-449568
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-449568
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر