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H-Y Antigen Incompatibility Not Associated with Adverse Immunologic Graft Outcomes : Deceased Donor Pair Analysis of the OPTN Database
المؤلفون المشاركون
Patrie, James T.
Keith, Douglas Scott
المصدر
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-10-15
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
H-Y antigen incompatibility adversely impacts bone marrow transplants however, the relevance of these antigens in kidney transplantation is uncertain.
Three previous retrospective studies of kidney transplant databases have produced conflicting results.
Methods.
This study analyzed the Organ Procurement and Transplantation Network database between 1997 and 2009 using male deceased donor kidney transplant pairs in which the recipient genders were discordant.
Death censored graft survival at six months, five, and ten years, treated acute rejection at six months and one year, and rates of graft failure by cause were the primary endpoints analyzed.
Results.
Death censored graft survival at six months was significantly worse for female recipients.
Analysis of the causes of graft failure at six months revealed that the difference in death censored graft survival was due primarily to nonimmunologic graft failures.
The adjusted and unadjusted death censored graft survivals at five and ten years were similar between the two genders as were the rates of immunologic graft failure.
No difference in the rates of treated acute rejection at six months and one year was seen between the two genders.
Conclusions.
Male donor to female recipient discordance had no discernable effect on immunologically mediated kidney graft outcomes in the era of modern immunosuppression.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Keith, Douglas Scott& Patrie, James T.. 2011. H-Y Antigen Incompatibility Not Associated with Adverse Immunologic Graft Outcomes : Deceased Donor Pair Analysis of the OPTN Database. Journal of Transplantation،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-449613
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Keith, Douglas Scott& Patrie, James T.. H-Y Antigen Incompatibility Not Associated with Adverse Immunologic Graft Outcomes : Deceased Donor Pair Analysis of the OPTN Database. Journal of Transplantation No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-449613
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Keith, Douglas Scott& Patrie, James T.. H-Y Antigen Incompatibility Not Associated with Adverse Immunologic Graft Outcomes : Deceased Donor Pair Analysis of the OPTN Database. Journal of Transplantation. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-449613
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-449613
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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