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Phylogenetic Analysis of Stenotrophomonas spp. Isolates Contributes to the Identification of Nosocomial and Community-Acquired Infections
المؤلفون المشاركون
Pasternak, Jacyr
Franzolin, Marcia Regina
Bando, Silvia Yumi
Cerezer, Vinicius Godoy
Moreira-Filho, Carlos Alberto
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-04-10
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Stenotrophomonas ssp.
has a wide environmental distribution and is also found as an opportunistic pathogen, causing nosocomial or community-acquired infections.
One species, S.
maltophilia, presents multidrug resistance and has been associated with serious infections in pediatric and immunocompromised patients.
Therefore, it is relevant to conduct resistance profile and phylogenetic studies in clinical isolates for identifying infection origins and isolates with augmented pathogenic potential.
Here, multilocus sequence typing was performed for phylogenetic analysis of nosocomial isolates of Stenotrophomonas spp.
and, environmental and clinical strains of S.
maltophilia.
Biochemical and multidrug resistance profiles of nosocomial and clinical strains were determined.
The inferred phylogenetic profile showed high clonal variability, what correlates with the adaptability process of Stenotrophomonas to different habitats.
Two clinical isolates subgroups of S.
maltophilia sharing high phylogenetic homogeneity presented intergroup recombination, thus indicating the high permittivity to horizontal gene transfer, a mechanism involved in the acquisition of antibiotic resistance and expression of virulence factors.
For most of the clinical strains, phylogenetic inference was made using only partial ppsA gene sequence.
Therefore, the sequencing of just one specific fragment of this gene would allow, in many cases, determining whether the infection with S.
maltophilia was nosocomial or community-acquired.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cerezer, Vinicius Godoy& Bando, Silvia Yumi& Pasternak, Jacyr& Franzolin, Marcia Regina& Moreira-Filho, Carlos Alberto. 2014. Phylogenetic Analysis of Stenotrophomonas spp. Isolates Contributes to the Identification of Nosocomial and Community-Acquired Infections. BioMed Research International،Vol. 2014, no. 2014, pp.1-13.
https://search.emarefa.net/detail/BIM-449874
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cerezer, Vinicius Godoy…[et al.]. Phylogenetic Analysis of Stenotrophomonas spp. Isolates Contributes to the Identification of Nosocomial and Community-Acquired Infections. BioMed Research International No. 2014 (2014), pp.1-13.
https://search.emarefa.net/detail/BIM-449874
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cerezer, Vinicius Godoy& Bando, Silvia Yumi& Pasternak, Jacyr& Franzolin, Marcia Regina& Moreira-Filho, Carlos Alberto. Phylogenetic Analysis of Stenotrophomonas spp. Isolates Contributes to the Identification of Nosocomial and Community-Acquired Infections. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-13.
https://search.emarefa.net/detail/BIM-449874
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-449874
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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