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Facing Contrast-Enhancing Gliomas : Perfusion MRI in Grade III and Grade IV Gliomas according to Tumor Area
المؤلفون المشاركون
Tomasello, Francesco
Frati, Alessandro
Rognone, Elisa
Bastianello, Stefano
Bergsland, Niels
Anna Luisa Di, Stefano
Berzero, Giulia
Ceroni, Mauro
Marchioni, Enrico
Farina, Lisa
Aquino, Domenico
Gastaldi, Matteo
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-04-03
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Tumoral neoangiogenesis characterizes high grade gliomas.
Relative Cerebral Blood Volume (rCBV), calculated with Dynamic Susceptibility Contrast (DSC) Perfusion-Weighted Imaging (PWI), allows for the estimation of vascular density over the tumor bed.
The aim of the study was to characterize putative tumoral neoangiogenesis via the study of maximal rCBV with a Region of Interest (ROI) approach in three tumor areas—the contrast-enhancing area, the nonenhancing tumor, and the high perfusion area on CBV map—in patients affected by contrast-enhancing glioma (grades III and IV).
Twenty-one patients were included: 15 were affected by grade IV and 6 by grade III glioma.
Maximal rCBV values for each patient were averaged according to glioma grade.
Although rCBV from contrast-enhancement and from nonenhancing tumor areas was higher in grade IV glioma than in grade III (5.58 and 2.68; 3.01 and 2.2, resp.), the differences were not significant.
Instead, rCBV recorded in the high perfusion area on CBV map, independently of tumor compartment, was significantly higher in grade IV glioma than in grade III (7.51 versus 3.78, P=0.036).
In conclusion, neoangiogenesis encompasses different tumor compartments and CBV maps appear capable of best characterizing the degree of neovascularization.
Facing contrast-enhancing brain tumors, areas of high perfusion on CBV maps should be considered as the reference areas to be targeted for glioma grading.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Anna Luisa Di, Stefano& Bergsland, Niels& Berzero, Giulia& Farina, Lisa& Rognone, Elisa& Gastaldi, Matteo…[et al.]. 2014. Facing Contrast-Enhancing Gliomas : Perfusion MRI in Grade III and Grade IV Gliomas according to Tumor Area. BioMed Research International،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-450154
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Anna Luisa Di, Stefano…[et al.]. Facing Contrast-Enhancing Gliomas : Perfusion MRI in Grade III and Grade IV Gliomas according to Tumor Area. BioMed Research International No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-450154
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Anna Luisa Di, Stefano& Bergsland, Niels& Berzero, Giulia& Farina, Lisa& Rognone, Elisa& Gastaldi, Matteo…[et al.]. Facing Contrast-Enhancing Gliomas : Perfusion MRI in Grade III and Grade IV Gliomas according to Tumor Area. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-450154
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-450154
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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