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Process Improvement by Eliminating Mixing of Whole Blood Units after an Overnight Hold Prior to Component Production Using the Buffy Coat Method
المؤلفون المشاركون
Levin, Elena
Yi, Qi-Long
Sheffield, William P.
Stewart, Tamiko
Jenkins, Craig
Hansen, Adele
Mastronardi, Cherie
Schubert, Peter
Lefresne, Wanda
Acker, Jason P.
Bhakta, Varsha
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-06-05
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
The elimination of a thorough manual mixing of whole blood (WB) which takes place following the overnight hold, but before the first centrifugation step, during buffy coat component production at Canadian Blood Services (CBS) was investigated.
WB was pooled after donation and split.
Pairs of platelet, red blood cell (RBC), and plasma components were produced, with half using the standard method and half using a method in which the mixing step was eliminated.
Quality assessments included yield, pH, CD62P expression and morphology for platelets, hemoglobin, hematocrit, hemolysis, and supernatant K+ for RBCs, and volume and factor VIII activity levels for plasma.
All components, produced using either method, met CBS quality control criteria.
There were no significant differences in platelet yield between components produced with and without mixing.
A significant difference was seen for RBC hemolysis at expiry (P=0.03), but for both groups, levels met quality control requirements.
Noninferiority of components produced without mixing was confirmed for all parameters.
Manual mixing is laborious and has a risk of repetitive strain for production staff and its significance is unclear.
Elimination of this step will improve process efficiencies without compromising quality.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mastronardi, Cherie& Schubert, Peter& Levin, Elena& Bhakta, Varsha& Yi, Qi-Long& Hansen, Adele…[et al.]. 2013. Process Improvement by Eliminating Mixing of Whole Blood Units after an Overnight Hold Prior to Component Production Using the Buffy Coat Method. Journal of Blood Transfusion،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-450197
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mastronardi, Cherie…[et al.]. Process Improvement by Eliminating Mixing of Whole Blood Units after an Overnight Hold Prior to Component Production Using the Buffy Coat Method. Journal of Blood Transfusion No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-450197
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mastronardi, Cherie& Schubert, Peter& Levin, Elena& Bhakta, Varsha& Yi, Qi-Long& Hansen, Adele…[et al.]. Process Improvement by Eliminating Mixing of Whole Blood Units after an Overnight Hold Prior to Component Production Using the Buffy Coat Method. Journal of Blood Transfusion. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-450197
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-450197
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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