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Acetaldehyde Content and Oxidative Stress in the Deleterious Effects of Alcohol Drinking on Rat Uterine Horn
المؤلفون المشاركون
Castro, José Alberto
Maciel, María Eugenia
Rodríguez de Castro, Carmen
Quintans, Leandro Néstor
Castro, Gerardo Daniel
Costantini, Martín Hernán
Fanelli, Silvia Laura
Buthet, Lara Romina
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-11-17
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
العلوم الطبية والصيدلة والعلوم الصحية
الطب البشري
الملخص EN
After alcohol exposure through a standard Lieber and De Carli diet for 28 days, a severe atrophy in the rat uteirne horn was observed, accompanied by significant alterations in its epithelial cells.
Microsomal pathway of acetaldehyde production was slightly increased.
Hydroxyl radicals were detected in the cytosolic fraction, and this was attributed to participation of xanthine oxidoreductase.
They were also observed in the microsomal fraction in the presence of NADPH generating system.
No generation of 1-hydroxyethyl was evidenced.
The t-butylhydroperoxide-induced chemiluminescence analysis of uterine horn homogenates revealed a significant increase in the chemiluminiscence emission due to ethanol exposure.
In the animals repeatedly exposed to alcohol, sulfhydryl content from uterine horn proteins was decreased, but no significant changes were observed in the protein carbonyl content from the same samples.
Minor but significant decreasing changes were observed in the GSH content accompanied by a tendency to decrease in the GSH/GSSG ratio.
A highly significant finding was the diminished activity content of glutathione peroxidase.
Results suggest that acetaldehyde accumulation plus the oxidative stress may play an additional effect to the alcohol-promoted hormonal changes in the uterus reported by others after chronic exposure to alcohol.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Buthet, Lara Romina& Maciel, María Eugenia& Quintans, Leandro Néstor& Rodríguez de Castro, Carmen& Costantini, Martín Hernán& Fanelli, Silvia Laura…[et al.]. 2013. Acetaldehyde Content and Oxidative Stress in the Deleterious Effects of Alcohol Drinking on Rat Uterine Horn. Journal of Toxicology،Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-450746
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Buthet, Lara Romina…[et al.]. Acetaldehyde Content and Oxidative Stress in the Deleterious Effects of Alcohol Drinking on Rat Uterine Horn. Journal of Toxicology No. 2013 (2013), pp.1-12.
https://search.emarefa.net/detail/BIM-450746
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Buthet, Lara Romina& Maciel, María Eugenia& Quintans, Leandro Néstor& Rodríguez de Castro, Carmen& Costantini, Martín Hernán& Fanelli, Silvia Laura…[et al.]. Acetaldehyde Content and Oxidative Stress in the Deleterious Effects of Alcohol Drinking on Rat Uterine Horn. Journal of Toxicology. 2013. Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-450746
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-450746
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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