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Anemia among HIV-Infected Patients Initiating Antiretroviral Therapy in South Africa : Improvement in Hemoglobin regardless of Degree of Immunosuppression and the Initiating ART Regimen
المؤلفون المشاركون
Sanne, Ian
Fox, Matthew P.
Takuva, Simbarashe
Maskew, Mhairi
Brennan, Alana T.
MacPhail, A. Patrick
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-08-27
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Among those with HIV, anemia is a strong risk factor for disease progression and death independent of CD4 count and viral load.
Understanding the role of anemia in HIV treatment is critical to developing strategies to reduce morbidity and mortality.
We conducted a prospective analysis among 10,259 HIV-infected adults initiating first-line ART between April 2004 and August 2009 in Johannesburg, South Africa.
The prevalence of anemia at ART initiation was 25.8%.
Mean hemoglobin increased independent of baseline CD4.
Females, lower BMI, WHO stage III/IV, lower CD4 count, and zidovudine use were associated with increased risk of developing anemia during follow-up.
After initiation of ART, hemoglobin improved, regardless of regimen type and the degree of immunosuppression.
Between 0 and 6 months on ART, the magnitude of hemoglobin increase was linearly related to CD4 count.
However, between 6 and 24 months on ART, hemoglobin levels showed a sustained overall increase, the magnitude of which was similar regardless of baseline CD4 level.
This increase in hemoglobin was seen even among patients on zidovudine containing regimens.
Since low hemoglobin is an established adverse prognostic marker, prompt identification of anemia may result in improved morbidity and mortality of patients initiating ART.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Takuva, Simbarashe& Maskew, Mhairi& Brennan, Alana T.& Sanne, Ian& MacPhail, A. Patrick& Fox, Matthew P.. 2013. Anemia among HIV-Infected Patients Initiating Antiretroviral Therapy in South Africa : Improvement in Hemoglobin regardless of Degree of Immunosuppression and the Initiating ART Regimen. Journal of Tropical Medicine،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-450875
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Takuva, Simbarashe…[et al.]. Anemia among HIV-Infected Patients Initiating Antiretroviral Therapy in South Africa : Improvement in Hemoglobin regardless of Degree of Immunosuppression and the Initiating ART Regimen. Journal of Tropical Medicine No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-450875
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Takuva, Simbarashe& Maskew, Mhairi& Brennan, Alana T.& Sanne, Ian& MacPhail, A. Patrick& Fox, Matthew P.. Anemia among HIV-Infected Patients Initiating Antiretroviral Therapy in South Africa : Improvement in Hemoglobin regardless of Degree of Immunosuppression and the Initiating ART Regimen. Journal of Tropical Medicine. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-450875
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-450875
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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