Parenteral Nutrition-Induced Cholestasis in Neonates : Where Does the Problem Lie?
المؤلفون المشاركون
Grenon, Renee
Montiveros, Carolina
Jolin-Dahel, Kheira
Barrowman, Nick
Ferretti, Emanuela
Jimenez-Rivera, Carolina
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-11-14
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Parenteral nutrition (PN) is an effective method of nourishing the neonate who is unable to receive full enteral feeds.
Cholestasis can be a complication of PN and can lead to severe liver damage.
Aim.
We describe our patient population and determine risk factors for developing PN cholestasis.
Methods.
Retrospective chart review of newborns admitted from January 2006 to May 2011 to the Neonatal Intensive Care Unit at our institution and received PN >14 days.
Cholestasis was defined as serum conjugated bilirubin >50 μmol/L.
Results.
Eighty-seven newborns were included; 18 (20.7%) developed PN cholestasis.
The most frequent surgical condition for both groups was gastroschisis (8/87; 9.2%).
No significant differences were found between the cholestasis and control groups for the following parameters: birth weight, gestational age, intrauterine growth restriction, Apgar scores, and day of life at initiation of enteral feeds.
Duration of PN in days and dosage of carbohydrates in g/kg/day were significantly higher in the cholestasis group than the control group.
Conclusion.
PN-related cholestasis presented in one-fifth of neonates receiving PN for more than two weeks.
Longer duration of PN and higher dosage of carbohydrates were independent risk factors for the development of PN cholestasis in this population.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jolin-Dahel, Kheira& Ferretti, Emanuela& Montiveros, Carolina& Grenon, Renee& Barrowman, Nick& Jimenez-Rivera, Carolina. 2013. Parenteral Nutrition-Induced Cholestasis in Neonates : Where Does the Problem Lie?. Gastroenterology Research and Practice،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-450932
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jolin-Dahel, Kheira…[et al.]. Parenteral Nutrition-Induced Cholestasis in Neonates : Where Does the Problem Lie?. Gastroenterology Research and Practice No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-450932
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jolin-Dahel, Kheira& Ferretti, Emanuela& Montiveros, Carolina& Grenon, Renee& Barrowman, Nick& Jimenez-Rivera, Carolina. Parenteral Nutrition-Induced Cholestasis in Neonates : Where Does the Problem Lie?. Gastroenterology Research and Practice. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-450932
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-450932
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر