Cardiac Autonomic Neuropathy Measured by Heart Rate Variability and Markers of Subclinical Atherosclerosis in Early Type 2 Diabetes
المؤلفون المشاركون
Fakhrzadeh, Husayn
Mirarefin, Mojde
Yamini-Sharif, Ahmad
Mohammadzadeh, Maryam
Badamchizadeh, Zohre
Tajalizadekhoob, Yaser
Sadeghian, Saeed
Sharifi, Farshad
Larijani, Bagher
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-12-04
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Cardiac autonomic neuropathy (CAN) is a critical complication of type 2 diabetes mellitus (T2DM).
Heart rate variability (HRV) is a noninvasive tool to assess cardiac autonomic function.
We aimed to evaluate whether CAN is associated with increased risk of atherosclerosis in T2DM.
A total of 57 diabetic and 54 nondiabetic subjects, free of coronary heart disease, were recruited.
Carotid intima media thickness (CIMT), coronary calcium score (CAC), and brachial Flow Mediated Dilation (FMD) were measured.
Heart rate variability and vagal components of autonomic function were determined.
Significant reduction of normalized HF power (P<0.05) and total power (P<0.01) was observed in T2DM.
CIMT and CAC scores were significantly higher while FMD was significantly lower in diabetics (P<0.01 for all).
Median HbA1c levels were significantly higher in diabetics.
CIMT was inversely and independently associated with total power both in diabetics and controls (P<0.01 for both groups).
There was also an inverse association between total power and median HbA1c.
Autonomic dysfunction, especially parasympathetic neuropathy, was present since early-stage T2DM.
This was related to subclinical atherosclerosis.
Early detection of cardiac autonomic neuropathy can help us detect the development of atherosclerosis earlier in T2DM to prevent unfavorable outcomes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fakhrzadeh, Husayn& Yamini-Sharif, Ahmad& Sharifi, Farshad& Tajalizadekhoob, Yaser& Mirarefin, Mojde& Mohammadzadeh, Maryam…[et al.]. 2012. Cardiac Autonomic Neuropathy Measured by Heart Rate Variability and Markers of Subclinical Atherosclerosis in Early Type 2 Diabetes. ISRN Endocrinology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-451302
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fakhrzadeh, Husayn…[et al.]. Cardiac Autonomic Neuropathy Measured by Heart Rate Variability and Markers of Subclinical Atherosclerosis in Early Type 2 Diabetes. ISRN Endocrinology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-451302
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fakhrzadeh, Husayn& Yamini-Sharif, Ahmad& Sharifi, Farshad& Tajalizadekhoob, Yaser& Mirarefin, Mojde& Mohammadzadeh, Maryam…[et al.]. Cardiac Autonomic Neuropathy Measured by Heart Rate Variability and Markers of Subclinical Atherosclerosis in Early Type 2 Diabetes. ISRN Endocrinology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-451302
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-451302
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر