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Breast Cancer Pathology, Receptor Status, and Patterns of Metastasis in a Rural Appalachian Population
المؤلفون المشاركون
Rose, David P.
Hobbs, Gerald R.
Hazard, Hannah
Kurian, Sobha
Vona-Davis, Linda
Ducatman, Barbara
Abraham, Jame
Gadiyaram, Vijaya
المصدر
Journal of Cancer Epidemiology
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-01-09
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Breast cancer patients in rural Appalachia have a high prevalence of obesity and poverty, together with more triple-negative phenotypes.
We reviewed clinical records for tumor receptor status and time to distant metastasis.
Body mass index, tumor size, grade, nodal status, and receptor status were related to metastatic patterns.
For 687 patients, 13.8% developed metastases to bone (n=42) or visceral sites (n=53).
Metastases to viscera occurred within five years, a latent period which was shorter than that for bone (P=0.042).
More women with visceral metastasis presented with grade 3 tumors compared with the bone and nonmetastatic groups (P=0.0002).
There were 135/574 women (23.5%) with triple-negative breast cancer, who presented with lymph node involvement and visceral metastases (68.2% versus 24.3%; P=0.033).
Triple-negative tumors that metastasized to visceral sites were larger (P=0.007).
Developing a visceral metastasis within 10 years was higher among women with triple-negative tumors.
Across all breast cancer receptor subtypes, the probability of remaining distant metastasis-free was greater for brain and liver than for lung.
The excess risk of metastatic spread to visceral organs in triple-negative breast cancers, even in the absence of positive nodes, was combined with the burden of larger and more advanced tumors.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Vona-Davis, Linda& Rose, David P.& Gadiyaram, Vijaya& Ducatman, Barbara& Hobbs, Gerald R.& Hazard, Hannah…[et al.]. 2014. Breast Cancer Pathology, Receptor Status, and Patterns of Metastasis in a Rural Appalachian Population. Journal of Cancer Epidemiology،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-451506
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Vona-Davis, Linda…[et al.]. Breast Cancer Pathology, Receptor Status, and Patterns of Metastasis in a Rural Appalachian Population. Journal of Cancer Epidemiology No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-451506
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Vona-Davis, Linda& Rose, David P.& Gadiyaram, Vijaya& Ducatman, Barbara& Hobbs, Gerald R.& Hazard, Hannah…[et al.]. Breast Cancer Pathology, Receptor Status, and Patterns of Metastasis in a Rural Appalachian Population. Journal of Cancer Epidemiology. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-451506
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-451506
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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