Endocrine Alterations Are the Main Determinants of Cardiac Remodelling in Restrictive Anorexia Nervosa
المؤلفون المشاركون
Senatore, Ignazio
Mercurio, Valentina
Affuso, Flora
Fazio, Valeria
Halinskaya, Irina
Ruvolo, Antonio
Fazio, Serafino
Carlomagno, Guido
المصدر
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-07-02
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Objective.
Anorexia nervosa is a condition of reduced hemodynamic load, characterized by varying degrees of cardiac remodelling, only in part related to reduced body mass; the mechanism for such variability, as well as its clinical significance, remains unknown.
Aim of the study was to assess the possible influence of a great number of clinical, biochemical, and endocrine factors on cardiovascular parameters in restrictive anorexia nervosa.
Method.
Twenty-five female patients hospitalized for restrictive anorexia nervosa underwent extensive cardiovascular, clinical, and biochemical evaluation.
Results.
Height-adjusted and cardiac workload-matched left ventricular mass was significantly related to several endocrine parameters, blood pressure, and vasoreactivity.
On multivariate analysis, IGF/GH ratio and systolic blood pressure were the only independent predictors of height-adjusted ventricular mass (adj-R2=0.585; P=0.001); when matching for cardiac workload, left ventricular mass was independently predicted only by GH and FT3 levels.
All effects were independent of patient's weight and BMI.
Conclusions.
Indices of endocrine impairment seem to be the most relevant determinants of left ventricular hypotrophy in anorectic patients, apparently independent of reduced hemodynamic load and BMI.
In particular, IGF/GH ratio and FT3 seem to particularly affect left ventricular mass in this population.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Carlomagno, Guido& Mercurio, Valentina& Ruvolo, Antonio& Senatore, Ignazio& Halinskaya, Irina& Fazio, Valeria…[et al.]. 2011. Endocrine Alterations Are the Main Determinants of Cardiac Remodelling in Restrictive Anorexia Nervosa. ISRN Endocrinology،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-451573
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Carlomagno, Guido…[et al.]. Endocrine Alterations Are the Main Determinants of Cardiac Remodelling in Restrictive Anorexia Nervosa. ISRN Endocrinology No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-451573
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Carlomagno, Guido& Mercurio, Valentina& Ruvolo, Antonio& Senatore, Ignazio& Halinskaya, Irina& Fazio, Valeria…[et al.]. Endocrine Alterations Are the Main Determinants of Cardiac Remodelling in Restrictive Anorexia Nervosa. ISRN Endocrinology. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-451573
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-451573
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر