Cadmium Exposure and Pancreatic Cancer in South Louisiana

المؤلفون المشاركون

Su, L. Joseph
Luckett, Brian G.
Rood, Jennifer C.
Fontham, Elizabeth T. H.

المصدر

Journal of Environmental and Public Health

العدد

المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-11، 11ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2012-12-24

دولة النشر

مصر

عدد الصفحات

11

التخصصات الرئيسية

الصحة العامة
الطب البشري

الملخص EN

Cadmium has been hypothesized to be a pancreatic carcinogen.

We test the hypothesis that cadmium exposure is a risk factor for pancreatic cancer with a population-based case-control study sampled from a population with persistently high rates of pancreatic cancer (south Louisiana).

We tested potential dietary and nondietary sources of cadmium for their association with urinary cadmium concentrations which reflect long-term exposure to cadmium due to the accumulation of cadmium in the kidney cortex.

Increasing urinary cadmium concentrations were significantly associated with an increasing risk of pancreatic cancer (2nd quartile OR = 3.34, 3rd = 5.58, 4th = 7.70; test for trend P≤0.0001).

Potential sources of cadmium exposure, as documented in the scientific literature, found to be statistically significantly associated with increased risk of pancreatic cancer included working as a plumber, pipefitter or welder (OR = 5.88) and high consumption levels of red meat (4th quartile OR = 6.18) and grains (4th quartile OR = 3.38).

Current cigarette smoking, at least 80 pack years of smoking, occupational exposure to cadmium and paints, working in a shipyard, and high consumption of grains were found to be statistically significantly associated with increased concentrations of urinary cadmium.

This study provides epidemiologic evidence that cadmium is a potential human pancreatic carcinogen.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Luckett, Brian G.& Su, L. Joseph& Rood, Jennifer C.& Fontham, Elizabeth T. H.. 2012. Cadmium Exposure and Pancreatic Cancer in South Louisiana. Journal of Environmental and Public Health،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-452291

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Luckett, Brian G.…[et al.]. Cadmium Exposure and Pancreatic Cancer in South Louisiana. Journal of Environmental and Public Health No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-452291

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Luckett, Brian G.& Su, L. Joseph& Rood, Jennifer C.& Fontham, Elizabeth T. H.. Cadmium Exposure and Pancreatic Cancer in South Louisiana. Journal of Environmental and Public Health. 2012. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-452291

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-452291