Neuropathology of AIDS : An Autopsy Review of 284 Cases from Brazil Comparing the Findings Pre- and Post-HAART (Highly Active Antiretroviral Therapy) and Pre- and Postmortem Correlation
المؤلفون المشاركون
Tostes, Sebastião
Silva-Vergara, Mário Leon
Micheletti, Adilha Misson Rua
Adad, Sheila Jorge
Silva, Ana Cristina Araújo Lemos
Meneses, Antonio Carlos Oliveira
Rodrigues, Blenda Sousa Carli
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-02-22
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
A retrospective study of central nervous system (CNS) in 284 autopsy AIDS cases in Brazil (1989–2008) divided into 3 groups: A (without antiretroviral treatment: 163 cases); B (other antiretroviral therapies: 76 cases); C (HAART for 3 months or more: 45 cases).
In 165 (58.1%) cases, relevant lesions were found, predominantly infections (54.2%); the most frequent was toxoplasmosis (29.9%) followed by cryptococcosis (15.8%), purulent bacterial infections (3.9%), and HIV encephalitis (2.8%); non-Hodgkin lymphomas occurred in 1.4% and vascular lesions in 1.1%.
There was no difference when compared the frequency of lesion among the groups; however, toxoplasmosis was less common while HIV encephalitis was more frequent in group C related to A.
CNS lesions remain a frequent cause of death in AIDS; however, the mean survival time was four times greater in group C than in A.
In 91 (55.1%) of 165 cases with relevant brain lesions (or 32% of the total 284 cases), there was discordance between pre- and postmortem diagnosis; disagreement type 1 (important disease that if diagnosed in life could change the patient prognosis) occurred in 49 (53.8%) of 91 discordant cases (17.6% of the total 284) indicating the autopsy importance, even with HAART and advanced diagnostics technologies.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Silva, Ana Cristina Araújo Lemos& Rodrigues, Blenda Sousa Carli& Micheletti, Adilha Misson Rua& Tostes, Sebastião& Meneses, Antonio Carlos Oliveira& Silva-Vergara, Mário Leon…[et al.]. 2012. Neuropathology of AIDS : An Autopsy Review of 284 Cases from Brazil Comparing the Findings Pre- and Post-HAART (Highly Active Antiretroviral Therapy) and Pre- and Postmortem Correlation. AIDS Research and Treatment،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-452919
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Silva, Ana Cristina Araújo Lemos…[et al.]. Neuropathology of AIDS : An Autopsy Review of 284 Cases from Brazil Comparing the Findings Pre- and Post-HAART (Highly Active Antiretroviral Therapy) and Pre- and Postmortem Correlation. AIDS Research and Treatment No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-452919
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Silva, Ana Cristina Araújo Lemos& Rodrigues, Blenda Sousa Carli& Micheletti, Adilha Misson Rua& Tostes, Sebastião& Meneses, Antonio Carlos Oliveira& Silva-Vergara, Mário Leon…[et al.]. Neuropathology of AIDS : An Autopsy Review of 284 Cases from Brazil Comparing the Findings Pre- and Post-HAART (Highly Active Antiretroviral Therapy) and Pre- and Postmortem Correlation. AIDS Research and Treatment. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-452919
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-452919
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر