Subcapsular Orchiectomy in the Primary Therapy of Patients with Bone Metastasis in Advanced Prostate Cancer : An Anachronistic Intervention?
المؤلفون المشاركون
Gilfrich, Christian
Peter, Julia
May, Matthias
Ahmed, Ali M.
Boeckmann, Wieland
Rud, Oleg
Fabricius, Paul G.
Kheyri, Reza
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-09-14
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Background.
The therapeutic impact of palliative androgen deprivation in metastatic prostate cancer is indisputable.
Bilateral orchiectomy represents the traditional method of AD but was reduced during the last years in favor for treatment with LHRH analogues.
Due to limited economic resources of the health care system, the economically priced definite surgical castration might experience a renaissance.
Methods.
In this single-center retrospective study, 83 consecutive patients with osseous metastasized prostate cancer were evaluated, who had primarily been treated by subcapsular bilateral orchiectomy.
Response to therapy, time until therapy failure, overall survival time, psychological disorders due to loss of organ, and disease-associated and postoperative surgical complications were recorded.
The median followup was 35 months (IQR: 26–46).
Results.
Patients' mean age at surgery was 72.1 (54–91) years.
Six patients (7.2%) displayed immediate tumor progression after orchiectomy.
Median time of tumor remission and overall survival time were 29 and 36 months, respectively.
14% of the study group showed minor postoperative complications.
No psychological problems occurred following bilateral orchiectomy.
Conclusion.
Due to an effective and persistent oncological effectiveness, less morbidity, and absence of psychological implications, bilateral subcapsular orchiectomy seems to be a practicable and advisable alternative in the first-line therapy of metastasized PCa.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Rud, Oleg& Peter, Julia& Kheyri, Reza& Gilfrich, Christian& Ahmed, Ali M.& Boeckmann, Wieland…[et al.]. 2011. Subcapsular Orchiectomy in the Primary Therapy of Patients with Bone Metastasis in Advanced Prostate Cancer : An Anachronistic Intervention?. Advances in Urology،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-453173
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rud, Oleg…[et al.]. Subcapsular Orchiectomy in the Primary Therapy of Patients with Bone Metastasis in Advanced Prostate Cancer : An Anachronistic Intervention?. Advances in Urology No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-453173
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Rud, Oleg& Peter, Julia& Kheyri, Reza& Gilfrich, Christian& Ahmed, Ali M.& Boeckmann, Wieland…[et al.]. Subcapsular Orchiectomy in the Primary Therapy of Patients with Bone Metastasis in Advanced Prostate Cancer : An Anachronistic Intervention?. Advances in Urology. 2011. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-453173
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-453173
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر