Medical Treatments for Endometriosis-Associated Pelvic Pain
المؤلفون المشاركون
Martinelli, Monica
Ricci, Giuseppe
Luppi, Stefania
Di Lorenzo, Giovanni
Zito, Gabriella
Giolo, Elena
Venturin, Irene
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-08-06
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
The main sequelae of endometriosis are represented by infertility and chronic pelvic pain.
Chronic pelvic pain causes disability and distress with a very high economic impact.
In the last decades, an impressive amount of pharmacological agents have been tested for the treatment of endometriosis-associated pelvic pain.
However, only a few of these have been introduced into clinical practice.
Following the results of the controlled studies available, to date, the first-line treatment for endometriosis associated pain is still represented by oral contraceptives used continuously.
Progestins represent an acceptable alternative.
In women with rectovaginal lesions or colorectal endometriosis, norethisterone acetate at low dosage should be preferred.
GnRH analogues may be used as second-line treatment, but significant side effects should be taken into account.
Nonsteroidal anti-inflammatory drugs are widely used, but there is inconclusive evidence for their efficacy in relieving endometriosis-associated pelvic pain.
Other agents such as GnRH antagonist, aromatase inhibitors, immunomodulators, selective progesterone receptor modulators, and histone deacetylase inhibitors seem to be very promising, but there is not enough evidence to support their introduction into routine clinical practice.
Some other agents, such as peroxisome proliferator activated receptors-γ ligands, antiangiogenic agents, and melatonin have been proven to be efficacious in animal studies, but they have not yet been tested in clinical studies.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zito, Gabriella& Luppi, Stefania& Giolo, Elena& Martinelli, Monica& Venturin, Irene& Di Lorenzo, Giovanni…[et al.]. 2014. Medical Treatments for Endometriosis-Associated Pelvic Pain. BioMed Research International،Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-453273
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zito, Gabriella…[et al.]. Medical Treatments for Endometriosis-Associated Pelvic Pain. BioMed Research International No. 2014 (2014), pp.1-12.
https://search.emarefa.net/detail/BIM-453273
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zito, Gabriella& Luppi, Stefania& Giolo, Elena& Martinelli, Monica& Venturin, Irene& Di Lorenzo, Giovanni…[et al.]. Medical Treatments for Endometriosis-Associated Pelvic Pain. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-453273
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-453273
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر