Exposure to Forced Swim Stress Alters Local Circuit Activity and Plasticity in the Dentate Gyrus of the Hippocampus
المؤلفون المشاركون
Maroun, Mouna
Yarom, Orli
Richter-Levin, Gal
المصدر
العدد
المجلد 2008، العدد 2008 (31 ديسمبر/كانون الأول 2008)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2008-02-14
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Studies have shown that, depending on its severity and context, stress can affect neural plasticity.
Most related studies focused on synaptic plasticity and long-term potentiation (LTP) of principle cells.
However, evidence suggests that following high-frequency stimulation, which induces LTP in principal cells, modifications also take place at the level of complex interactions with interneurons within the dentate gyrus, that is, at the local circuit level.
So far, the possible effects of stress on local circuit activity and plasticity were not studied.
Therefore, we set out to examine the possible alterations in local circuit activity and plasticity following exposure to stress.
Local circuit activity and plasticity were measured by using frequency dependant inhibition (FDI) and commissural modulation protocols following exposure to a 15 minute-forced swim trial.
Exposure to stress did not alter FDI.
The application of theta-burst stimulation (TBS) reduced FDI in both control and stressed rats, but this type of plasticity was greater in stressed rats.
Commissural-induced inhibition was significantly higher in stressed rats both before and after applying theta-burst stimulation.
These findings indicate that the exposure to acute stress affects aspects of local circuit activity and plasticity in the dentate gyrus.
It is possible that these alterations underlie some of the behavioral consequences of the stress experience.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yarom, Orli& Maroun, Mouna& Richter-Levin, Gal. 2008. Exposure to Forced Swim Stress Alters Local Circuit Activity and Plasticity in the Dentate Gyrus of the Hippocampus. Neural Plasticity،Vol. 2008, no. 2008, pp.1-8.
https://search.emarefa.net/detail/BIM-453482
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yarom, Orli…[et al.]. Exposure to Forced Swim Stress Alters Local Circuit Activity and Plasticity in the Dentate Gyrus of the Hippocampus. Neural Plasticity No. 2008 (2008), pp.1-8.
https://search.emarefa.net/detail/BIM-453482
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yarom, Orli& Maroun, Mouna& Richter-Levin, Gal. Exposure to Forced Swim Stress Alters Local Circuit Activity and Plasticity in the Dentate Gyrus of the Hippocampus. Neural Plasticity. 2008. Vol. 2008, no. 2008, pp.1-8.
https://search.emarefa.net/detail/BIM-453482
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-453482
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر