Insights into Neonatal Oral Feeding through the Salivary Transcriptome
المؤلف
المصدر
International Journal of Pediatrics
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-07-10
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
The development of safe and effective oral feeding skills in the newborn is complex and may be associated with significant morbidities.
Our understanding of neonatal oral feeding maturation at the molecular level is limited, providing an opportunity to utilize emerging molecular techniques to accurately assess neonatal oral feeding skills.
Objective.
To identify key regulatory genes in neonatal saliva involved in successful oral feeding.
Methods.
Previously, our laboratory identified 9,286 genes in saliva that statistically significantly altered their gene expression as premature newborns gained advanced oral feeding skills.
In this report, genes previously identified underwent an updated and targeted pathway analysis with Ingenuity Pathway Analysis (IPA) to identify potential candidate genes involved in successful oral feeding.
Genes were considered if they were in the five most significantly up- and down-regulated physiological pathways and were associated with the keywords “feeding”, “digestion” and “development”.
Results.
There were 2,186 genes that met criteria.
Pathways associated with feeding behavior, cranial nerve development, and the development of the nervous, skeletal, and muscular systems were highlighted.
Discussion.
These data provide important insights into the biological processes involved in oral feeding in the newborn at a molecular level and identify novel pathways associated with successful oral feeding.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Maron, Jill L.. 2012. Insights into Neonatal Oral Feeding through the Salivary Transcriptome. International Journal of Pediatrics،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-453581
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Maron, Jill L.. Insights into Neonatal Oral Feeding through the Salivary Transcriptome. International Journal of Pediatrics No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-453581
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Maron, Jill L.. Insights into Neonatal Oral Feeding through the Salivary Transcriptome. International Journal of Pediatrics. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-453581
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-453581
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر