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The Association between Yang-Deficient Constitution and Clinical Outcome of Highly Active Antiretroviral Therapy on People Living with HIV
المؤلفون المشاركون
Xu, Feilong
Leung, Ross Ka-kit
Zhang, Jiansheng
Jia, Weidong
Zhang, Fuchun
Tan, Xinghua
Cen, Yuwen
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-12-30
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Objective.
To determine the association between Yang-Deficient Constitution and the clinical outcomes of HIV/AIDS patients who have initiated highly active antiretroviral therapy (HAART).
Method.
A total of 197 antiretroviral-naive adults who initiated HAART between 2009 and 2011 were recruited.
The participants were asked to complete a questionnaire twice to assess their Yang-Deficient Constitution status before HAART.
During the study, signs and symptoms and CD4 or CD8 T cell counts were recorded.
Routine blood and biochemical tests were conducted.
For the patients who were found to have infections, pathologic examination was performed.
Statistical test of association of clinical attributes and demographic factors with Yang-Deficient Constitution was conducted.
Result.
Good test-retest reliability was observed for Yang-Deficient Constitution scoring.
The median Yang-Deficient Constitution score of 142 eligible participants was 25.
Female (score = 32.14, P<0.05), hepatotoxicity (32.14, P<0.1), nephrotoxicity (37.50, P<0.1), total number of adverse events (P<0.1), and mortality (39.29, P<0.05) were associated with Yang-Deficient Consitution, while annual changes or nadir values of CD4 or CD8 T lymphocytes, and newly acquired infections after starting HAART were not.
Mortality was also associated with total number of adverse events (P<0.05), hepatotoxicity (P<0.05), and nephrotoxicity (P<0.05).
Conclusion.
Yang-Deficient Constitution score has a potential to be developed as a predictor for early HIV-related mortality and side effects.
The interrelation and underlying mechanisms should be further investigated for evidence-based design of a more appropriate treatment strategy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cen, Yuwen& Leung, Ross Ka-kit& Zhang, Fuchun& Jia, Weidong& Zhang, Jiansheng& Tan, Xinghua…[et al.]. 2013. The Association between Yang-Deficient Constitution and Clinical Outcome of Highly Active Antiretroviral Therapy on People Living with HIV. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-454037
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cen, Yuwen…[et al.]. The Association between Yang-Deficient Constitution and Clinical Outcome of Highly Active Antiretroviral Therapy on People Living with HIV. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-454037
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cen, Yuwen& Leung, Ross Ka-kit& Zhang, Fuchun& Jia, Weidong& Zhang, Jiansheng& Tan, Xinghua…[et al.]. The Association between Yang-Deficient Constitution and Clinical Outcome of Highly Active Antiretroviral Therapy on People Living with HIV. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-454037
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-454037
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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