Evaluation of the Potential Sensitization of Chlorogenic Acid : A Meta-Analysis
المؤلفون المشاركون
Lin, Mingbao
Chen, Qian
Wang, Yingchao
Fan, Xiaohui
Gong, Wan
Sun, Lijuan
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-05-16
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Chlorogenic acid (CGA) widely exists in many plants, which are used as medicinal substances in traditional Chinese medicine injectables (TCMIs) that have been widely applied in clinical treatments.
However, it is still controversial whether CGA is responsible for TCMIs-related hypersensitivity.
Several studies have been performed to evaluate its potential sensitization property, but the results were inconclusive.
Therefore, the aim of this study was to evaluate its potential sensitization systematically using meta-analysis based on data extracted from literatures, searching databases of PubMed, EMBASE, ISI Web of Knowledge, CNKI, VIP, and CHINAINFO from January 1979 to October 2012, a total of 108 articles were retrieved by electronic search strategy, out of which 13 studies met the inclusion criteria.
In ASA test, odds ratio of behavior changes was 4.33 (1.62, 11.60), showing significant changes after CGA treatment (P=0.004).
Serum IgG, serum histamine, PLN cellularity, and IgG1 AFCs were significantly enhanced after CGA treatment (P<0.05).
Totally, these results indicated that CGA could induce a positive reaction in potential sensitization, and intravenous administration of it might be a key factor for sensitization triggering, which could at least warrant more careful application of TCMIs containing CGA in clinical practices.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lin, Mingbao& Gong, Wan& Chen, Qian& Sun, Lijuan& Wang, Yingchao& Fan, Xiaohui. 2013. Evaluation of the Potential Sensitization of Chlorogenic Acid : A Meta-Analysis. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-454654
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lin, Mingbao…[et al.]. Evaluation of the Potential Sensitization of Chlorogenic Acid : A Meta-Analysis. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-454654
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lin, Mingbao& Gong, Wan& Chen, Qian& Sun, Lijuan& Wang, Yingchao& Fan, Xiaohui. Evaluation of the Potential Sensitization of Chlorogenic Acid : A Meta-Analysis. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-454654
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-454654
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر