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Treatment with at Homeopathic Complex Medication Modulates Mononuclear Bone Marrow Cell Differentiation
المؤلفون المشاركون
Oliveira, Carolina Camargo
Gabardo, Juarez
Guimarães, Fernando S. F.
Cardoso, Francolino
de Freitas Buchi, Dorly
Abud, Ana Paula R.
Cesar, Beatriz
Bernardi, Raffaello Popa Di
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-02-17
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
A homeopathic complex medication (HCM), with immunomodulatory properties, is recommended for patients with depressed immune systems.
Previous studies demonstrated that the medication induces an increase in leukocyte number.
The bone marrow microenvironment is composed of growth factors, stromal cells, an extracellular matrix and progenitor cells that differentiate into mature blood cells.
Mice were our biological model used in this research.
We now report in vivo immunophenotyping of total bone marrow cells and ex vivo effects of the medication on mononuclear cell differentiation at different times.
Cells were examined by light microscopy and cytokine levels were measured in vitro.
After in vivo treatment with HCM, a pool of cells from the new marrow microenvironment was analyzed by flow cytometry to detect any trend in cell alteration.
The results showed decreases, mainly, in CD11b and TER-119 markers compared with controls.
Mononuclear cells were used to analyze the effects of ex vivo HCM treatment and the number of cells showing ring nuclei, niche cells and activated macrophages increased in culture, even in the absence of macrophage colony-stimulating factor.
Cytokines favoring stromal cell survival and differentiation in culture were induced in vitro.
Thus, we observe that HCM is immunomodulatory, either alone or in association with other products.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cesar, Beatriz& Abud, Ana Paula R.& Oliveira, Carolina Camargo& Cardoso, Francolino& Bernardi, Raffaello Popa Di& Guimarães, Fernando S. F.…[et al.]. 2011. Treatment with at Homeopathic Complex Medication Modulates Mononuclear Bone Marrow Cell Differentiation. Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-454924
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cesar, Beatriz…[et al.]. Treatment with at Homeopathic Complex Medication Modulates Mononuclear Bone Marrow Cell Differentiation. Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-10.
https://search.emarefa.net/detail/BIM-454924
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cesar, Beatriz& Abud, Ana Paula R.& Oliveira, Carolina Camargo& Cardoso, Francolino& Bernardi, Raffaello Popa Di& Guimarães, Fernando S. F.…[et al.]. Treatment with at Homeopathic Complex Medication Modulates Mononuclear Bone Marrow Cell Differentiation. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-454924
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-454924
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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